Phase 3 Ovarian Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with epithelial ovarian cancer, confirmed by a laboratory examination of tissue
• People whose cancer has been classified at a specific stage: FIGO Stage Ia or Ib (Grade 2 or 3, or a type called clear cell carcinoma), or FIGO Stage Ic(b) (any grade or type) (confirm with trial site if stage is unclear)
• People whose cancer stage was confirmed through a thorough surgical procedure called comprehensive staging or restaging surgery
• People who had a full staging surgery that included removal of the uterus, both ovaries and fallopian tubes, and the omentum (a layer of tissue in the abdomen), along with fluid sampling, tissue biopsies from the lining of the abdomen, and removal of lymph nodes in the back of the abdomen — with some exceptions allowed if certain steps were not fully completed for documented reasons
• People aged 20 or older
• People with a general health and activity level rated at 0 or 1 on a standard scale used by doctors (meaning fully active or able to carry out light activity)
• People who have not yet received any treatment for the cancer after surgery
• People for whom the first study treatment can begin within 8 weeks of the staging surgery
• People whose organs (such as kidneys, liver, and bone marrow) are functioning at an acceptable level
• People who have given written informed consent to participate

Who may not be able to join:

• People whose cancer is classified as FIGO Stage Ic(a), Ic(1), or Ic(2)
• People whose tumour contains sarcoma elements (a particular type of cancer cell)
• People who show signs of interstitial pneumonia (a type of lung inflammation) or pulmonary fibrosis (scarring of the lungs) on chest X-ray or CT scan
• People who have serious other medical conditions
• People who have an active infection at the time of joining
• People who have a condition where the bowel is not moving properly, or a bowel blockage
• People who currently have another cancer, or who had a different cancer within the past 5 years
• People who have previously received chemotherapy or radiation therapy
• People with a history of serious allergic reactions to medications
• People who have moderate to severe nerve damage affecting movement or sensation (graded 2, 3, or 4 on a standard medical scale)
• People who have previously had an allergic reaction to polyoxyethylated or hydrogenated castor oil (substances used in some medications)
• People who test positive for a specific marker of Hepatitis B infection (HBsAg), or who have certain levels of Hepatitis B virus detected in their blood alongside other Hepatitis B markers
• People who the treating doctor considers unsuitable for the trial for any safety reason

Important: Always verify eligibility with the trial site directly before applying.