Pulmonary Hypertension Trial, Recruiting NCT04078243 Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust Condition: Pulmonary Hypertension
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Pulmonary Hypertension Trial, Recruiting

NCT04078243
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with pulmonary hypertension (high blood pressure in the lungs), in any of the main types (Groups I, II, III, or IV)
  • People who are 18 years of age or older
  • People whose kidneys are functioning above a certain level, based on a blood test result called eGFR being greater than 25 (confirm with trial site)
  • People with a body mass index (a measure of body weight relative to height) below 35
  • People who have a pulmonary artery branch measuring at least 7mm in size (confirm with trial site)
  • Women of childbearing age who have a negative pregnancy test
  • People who have given written agreement to take part in the trial
  • People who are willing to follow the requirements of the trial

Who may not be able to join:

  • People whose pulmonary hypertension is classified as Group IV (a specific type caused by blood clots)
  • People who currently have an active infection
  • People who have a blood clot in the lung (pulmonary embolus) or a blood clot in a deep vein (deep vein thrombosis)
  • People who have had a major heart or cardiovascular event within the past 2 months
  • People who have had a specific type of heart device called a cardiac resynchronisation therapy (CRT) device fitted within the past 3 months
  • People who have a mechanical valve on the right side of their heart
  • People with a known disorder affecting how their blood clots
  • People with a known allergy or sensitivity to aspirin or clopidogrel (common blood-thinning medications)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: 0114 2509550

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Sheffield Teaching Hospitals NHS Foundation Trust
Registry
ClinicalTrials.gov
Start date
21 January 2020
Est. completion
6 January 2028

Where this trial is recruiting

🇬🇧 United Kingdom

Primary endpoints

Activity Monitors

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov