Phase 2 Breast Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Women between 18 and 70 years old
• People whose breast cancer has been confirmed by a tissue sample (biopsy) to be a primary invasive breast cancer
• People whose breast cancer has been confirmed by a tissue sample to be triple negative breast cancer
• People who are planning to have treatment before surgery (neoadjuvant therapy) and whose tumour is larger than 2 cm
• People from whom blood samples and five sections of tumour tissue can be collected before treatment begins, and blood samples can be collected at the time of surgery
• People who have at least one tumour that can be measured using standard imaging criteria
• People who are largely able to carry out daily activities with no more than minor limitations (confirm with trial site)
• People whose heart pumping function measures 55% or above on testing
• People whose bone marrow is producing enough blood cells — specifically, neutrophils, platelets, and haemoglobin must each be above a minimum level (confirm with trial site for exact values)
• People whose kidneys and liver are functioning within acceptable ranges, based on blood test results (confirm with trial site for exact values)
• People who are willing and able to follow the planned treatment schedule, understand the research process, and have signed a consent form

Who may not be able to join:

• People who have previously received chemotherapy, hormone therapy, biological therapy, or radiotherapy for their cancer
• People with moderate or severe heart disease as rated by a standard medical scoring system
• People with a serious ongoing infection or other severe health conditions
• People who are allergic to or unable to tolerate the chemotherapy drugs or their ingredients used in the trial
• People who have had another cancer in the past five years, with the exception of certain cured skin cancers or cervical carcinoma in situ
• People who are pregnant or breastfeeding, or people of reproductive age who are unwilling to use appropriate contraception during the trial
• People who have participated in another clinical trial or received an experimental treatment within 30 days before the first dose of this trial
• People whom the trial researchers consider unsuitable for participation for any other reason

Important: Always verify eligibility with the trial site directly before applying.