COPD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have been diagnosed with moderate-to-severe obstructive sleep apnea (a condition where breathing repeatedly stops during sleep), confirmed by an overnight sleep study showing 20 or more breathing interruptions per hour
- People who also have moderate-to-severe COPD (a serious lung condition), confirmed by breathing/lung function tests
- People with a significant smoking history of more than 10 pack-years (confirm with trial site for exact calculation)
- Both men and women are eligible
- People aged 60 years or older
- People whose COPD treatment has been stable and consistent
Who may not be able to join:
- People who are currently using or have previously used a PAP machine (such as a CPAP) or a dental/oral device for sleep apnea
- People whose sleep apnea is mainly caused by signals from the brain (called central sleep apnea) rather than physical airway blockage
- People with a known disease affecting the muscles or nerves (neuromuscular disease)
- People with conditions that may affect thinking and memory, including brain-degenerating diseases, traumatic brain injury, untreated PTSD, or a history of learning disability
- People taking medications that affect sleepiness or alertness, such as sleeping tablets or stimulants
- People who are actively suicidal or have an unstable mental health condition
- People with a very high sleepiness score (above 16 on the Epworth scale), or who have had a near-miss or actual car accident due to sleepiness in the past 12 months
- People whose primary sleep disorder is narcolepsy requiring stimulant medication
- People who work as commercial drivers or operate heavy machinery
- People who use supplemental oxygen for more than 12 hours per day before the study begins
- People who are unable to wear a nasal or face mask, for example due to facial injuries or claustrophobia
- People who drink more than 3 alcoholic beverages per day, or who currently use certain illicit drugs
- People who are unable to give informed consent
- People currently receiving hospice/end-of-life care
- Women who are pregnant
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Susmita Chowdhuri, MD MS, John D. Dingell VA Medical Center, Detroit, MI
Phone: (313) 576-4464
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Neurocognitive function Trails A and Trails B; Neurocognitive function PASAT; Neurocognitive function Stroop color-word interference; Neurocognitive function DIGIT; Neurocognitive function WASI; Neurocognitive function WMS; Neurocognitive function PVT; Neurocognitive function HVLT-R; Sleepiness ESS; Sleep quality PSQI; Quality of life SF-36v2; Quality of life FOSQ; Quality of life SGRQ
Can't join this trial?
Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.