Phase 2 Motor Neurone Disease Trial, Recruiting NCT04244630 Sponsor: Dallas VA Medical Center Condition: Motor Neurone Disease
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Phase 2 Motor Neurone Disease Trial, Recruiting

NCT04244630
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with ALS (also known as Lou Gehrig's disease) by a study doctor, confirmed through specific diagnostic criteria.
  • People who are between 21 and 80 years of age (inclusive).
  • People who are taking the ALS medication riluzole must have been on a stable, unchanged dose for at least 30 days before the first study visit.
  • People who are willing and able to read and sign a consent form that has been reviewed and approved by an ethics review board.

Who may not be able to join:

  • People who have been diagnosed with another brain or nervous system disease, such as Parkinson's disease or Alzheimer's disease.
  • People who have had a serious or unstable medical condition in the past 30 days, such as unstable chest pain or advanced cancer.
  • People who have HIV (human immunodeficiency virus).
  • People who do not have the mental capacity to sign a consent form or follow the study procedures.
  • People who have a recent history of alcohol or drug misuse, or who have not followed instructions in previous medical treatments or research studies.
  • People who have taken part in another clinical trial or received an experimental medication within the past 30 days.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Olaf Stuve, M.D., Ph.D., Dallas VA Medical Center

Phone: 214-648-7244

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Dallas VA Medical Center
Registry
ClinicalTrials.gov
Start date
2 November 2023
Est. completion
1 December 2025

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Measurement of serum NfL

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov