Osteoarthritis Trial, Recruiting NCT04275362 Sponsor: More Foundation Condition: Osteoarthritis
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Osteoarthritis Trial, Recruiting

NCT04275362
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

If you are a healthy volunteer (Control):

  • You are 50 years of age or older.
  • You are willing to sign a consent form agreeing to have your walking movement recorded and analyzed.

If you have already had knee replacement surgery (Retrospective):

  • You previously had a total knee replacement using either a Stryker Triathlon or Biomet Vanguard knee implant system.
  • You were at least 50 years old at the time of your knee replacement surgery.
  • You previously signed a consent form for walking movement data collection under an approved research board.
  • Your surgery followed the standard guidelines for the knee implant used.

If you are planning to have knee replacement surgery (Prospective):

  • You have been identified as a suitable candidate for the DJO Global Empowr total knee replacement.
  • You are at least 50 years old at the time of your knee replacement surgery.
  • You are willing to sign a consent form agreeing to have your walking movement recorded and analyzed.
  • Your surgery will follow the standard guidelines for the knee implant used.

Who may not be able to join:

Healthy volunteers (Controls):

  • You have any injury or condition affecting your muscles, bones, or joints.
  • You are pregnant or planning to become pregnant.
  • Your Body Mass Index (BMI) is over 40 (confirm with trial site).

Those who have had or are planning knee replacement surgery (Retrospective & Prospective):

  • You have inflammatory arthritis or psoriatic arthritis.
  • You are pregnant or planning to become pregnant.
  • Your BMI is over 40 (confirm with trial site).
  • You had an active or suspected hidden infection in or around the knee joint at the time of surgery.
  • The bone around your knee joint was too weak or damaged to properly support a knee implant.
  • You have a mental health or nerve/muscle condition that could increase the risk of the implant failing or cause complications during recovery (confirm with trial site).
  • You have severe knee instability due to damaged or missing ligaments on the sides of your knee.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Scott Siverhus, MD, The CORE Institute

Phone: 623.241.5472

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
More Foundation
Registry
ClinicalTrials.gov
Start date
2 February 2017
Est. completion
2 April 2023

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Knee flexion angle during swing; Knee flexion angle during swing; Knee flexion angle during swing; Knee flexion angle during stance; Knee flexion angle during stance; Knee flexion angle during stance; Knee adduction angle during stance; Knee adduction angle during stance; Knee adduction angle during stance; Knee flexion moment; Knee flexion moment; Knee flexion moment; Knee adduction moment; Knee adduction moment; Knee adduction moment; Knee power; Knee power; Knee power; Vertical GRF; Vertical GRF; Vertical GRF; AP GRF; AP GRF; AP GRF; ML GRF; ML GRF; ML GRF

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov