Vasculitis Trial, Recruiting (NCT04278404)

Vasculitis Trial, Recruiting NCT04278404 Sponsor: Duke University Condition: Vasculitis

Printed from Voxsanity (voxsanity.com.au) — NCT04278404 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Vasculitis

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are under 21 years of age
A parent, legal guardian, or the participant themselves (if an adult) understands and is willing to sign a consent form agreeing to take part
Either you are currently taking one or more of the specific medications being studied, OR you are not taking those medications but have tested positive for COVID-19 (SARS-CoV-2) within the past 60 days

Who may not be able to join:

You are currently pregnant
You have had dialysis (a kidney-filtering treatment) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have had a kidney transplant in the past 30 days (applies only to participants currently taking one of the study medications)
You have had a liver transplant in the past year (applies only to participants currently taking one of the study medications)
You have had a stem cell transplant in the past year (applies only to participants currently taking one of the study medications)
You have undergone therapeutic hypothermia (a treatment that deliberately lowers body temperature) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have had plasmapheresis (a procedure that filters the blood) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have a ventricular assist device (a mechanical pump that helps the heart) (applies only to participants currently taking one of the study medications)
The study doctor feels that, for any reason, taking part would not be appropriate for you (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 27 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Chi Hornik, Duke Clinical Research Institute

Phone: (919) 260-7626

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT04278404

Sponsor: Duke University

Phase: Not Applicable

Status: Recruiting

Condition: Vasculitis

Trial contact: (919) 260-7626

More information: https://clinicaltrials.gov/study/NCT04278404

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are under 21 years of age
A parent, legal guardian, or the participant themselves (if an adult) understands and is willing to sign a consent form agreeing to take part
Either you are currently taking one or more of the specific medications being studied, OR you are not taking those medications but have tested positive for COVID-19 (SARS-CoV-2) within the past 60 days

Who may not be able to join:

You are currently pregnant
You have had dialysis (a kidney-filtering treatment) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have had a kidney transplant in the past 30 days (applies only to participants currently taking one of the study medications)
You have had a liver transplant in the past year (applies only to participants currently taking one of the study medications)
You have had a stem cell transplant in the past year (applies only to participants currently taking one of the study medications)
You have undergone therapeutic hypothermia (a treatment that deliberately lowers body temperature) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have had plasmapheresis (a procedure that filters the blood) in the past 24 hours (applies only to participants currently taking one of the study medications)
You have a ventricular assist device (a mechanical pump that helps the heart) (applies only to participants currently taking one of the study medications)
The study doctor feels that, for any reason, taking part would not be appropriate for you (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 27 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Duke University

Registry

ClinicalTrials.gov

Start date

5 March 2020

Est. completion

1 March 2027

Where this trial is recruiting

🇨🇦 Canada 🇺🇸 United States

Primary endpoints

Clearance (CL) or apparent oral clearance (CL/F) as measured by PK sampling; Volume of distribution (V) or apparent oral volume of distribution (V/F) as measured by PK sampling; Elimination rate constant (ke) as measured by PK sampling; Half-life (t1/2) as measured by PK sampling; Absorption rate constant (ka) as measured by PK sampling; AUC (area under the curve) as measured by PK sampling; Maximum concentration (Cmax) as measured by PK sampling; Time to achieve maximum concentration (Tmax) as measured by PK sampling

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov