Stroke Trial, Recruiting NCT04312126 Sponsor: National Institute of Neurological Disorders and Stroke (NINDS) Condition: Stroke
Back to Stroke

Stroke Trial, Recruiting

NCT04312126
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Healthy Volunteers:

  • You are between 18–35 years old (Group 1) or between 50–80 years old (Group 2)
  • You speak English
  • You are strongly right-hand dominant (you almost always use your right hand for tasks)
  • You have a normal neurological exam as confirmed by the study doctor

Stroke Patients:

  • You are 18 years old or older
  • You are willing and able to give your own consent to participate
  • You had a stroke at least 6 months ago that affected one or both of your arms at the time of diagnosis
  • You are able to perform the required study tasks, as checked during a physical exam
  • You speak English

Who may not be able to join:

Healthy Volunteers:

  • You are currently pregnant
  • You have any reason you cannot safely have an MRI or MEG brain scan (confirm with trial site)
  • You have taken sleep medications within 24 hours before a study session
  • You have a serious or worsening neurological, psychological, or medical condition, as determined by the study doctor
  • You are a staff member from the specific NIH section running this study

Stroke Patients:

  • You are currently pregnant
  • You have had a large stroke affecting the brainstem or cerebellum, as determined by the study doctor
  • You have a serious or worsening neurological condition other than stroke (for example, Parkinson's disease or multiple sclerosis)
  • You have an uncontrolled heart, lung, kidney, digestive, metabolic, psychiatric, sleep, or hormone-related condition
  • You have any reason you cannot safely have an MRI or MEG brain scan (confirm with trial site)
  • You are a staff member from the specific NIH section running this study

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Leonardo G Cohen, M.D., National Institute of Neurological Disorders and Stroke (NINDS)

Phone: (301) 496-4000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
4 March 2021
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

The primary endpoint measure is the degree to which motor skill consolidation (i.e., offline change in correct sequence typing speed) is predicted by replay rates during wakeful rest and sleep, and spindle rates during sleep (i.e. multiple r...

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov