Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are over 18 years old
• People who have had their first stroke affecting one side of the brain, with the stroke occurring more than 3 months ago
• People who still have walking difficulties affecting one side of the body as a result of their stroke (such as an abnormal walking pattern)
• People who are able to walk for 5 minutes at their own pace, with or without a walking aid such as a cane
• People whose walking speed is slower than 1.2 metres per second
• People whose lower limb movement and motor function falls within a specific range on a clinical assessment scale called the Fugl-Meyer Motor Score (a score between 15 and 30) (confirm with trial site)
• People who have at least 5 degrees of upward ankle movement, which is needed to complete a specific ankle movement task used in the trial (confirm with trial site)

Who may not be able to join:

• People with severe osteoporosis
• People whose lower limb movement is significantly limited due to muscle or joint stiffness (contractures)
• People with notably increased muscle stiffness in the ankle, as measured by a clinical scale called the Modified Ashworth Scale (a score above 2) (confirm with trial site)
• People whose anti-spasticity medications (medicines used to reduce muscle stiffness) are not stable or are being changed during the study period
• People with reduced sensation in the lower limb, as measured by the Fugl-Meyer Sensory Assessment Scale (a score below 6) (confirm with trial site)
• People with heart, lung, or metabolic conditions such as irregular heartbeat, uncontrolled high blood pressure, uncontrolled diabetes, or chronic lung disease
• People with unhealed pressure sores or an ongoing infection
• People with significant difficulties with memory, thinking, or communication that may prevent them from understanding or completing the study tasks, as assessed by a cognitive screening tool called the Mini-Mental State Examination (a score below 21) (confirm with trial site)
• People whose stroke affected the brainstem or cerebellum (specific regions at the base and back of the brain)
• People who do not pass a supervised exercise stress test conducted before the trial begins
• People who have an implanted cardiac pacemaker (a device fitted in the chest to regulate heartbeat)
• People who have any metal implants in the head or face
• People who experience unexplained, recurring headaches
• People with a history of seizures or epilepsy
• People currently taking medications that may increase brain excitability or lower the threshold for seizures
• People with skull abnormalities or fractures
• People who have had a concussion within the last 6 months
• People who are currently pregnant
• People with skin sensitivity or allergies that affect the scalp or skin
• People with a history of contact dermatitis (a skin reaction caused by touching certain substances)
• People with a history of allodynia (pain from normally non-painful stimuli) or hyperalgesia (increased sensitivity to pain)
• People with any other skin or scalp condition that could be made worse by electrical stimulation applied to the scalp

Important: Always verify eligibility with the trial site directly before applying.