Breast Cancer Trial, Recruiting NCT04486495 Sponsor: Maastricht University Medical Center Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT04486495
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women who have invasive breast cancer in one breast only, with cancer that has spread to nearby lymph nodes in the armpit (rated cN1 to cN3 on medical staging).
  • People whose lymph node involvement has been confirmed through a biopsy or similar test.
  • People who are planned to receive chemotherapy before surgery (sometimes combined with immunotherapy), followed by assessment and treatment of the breast and armpit area.

Who may not be able to join:

  • People whose lymph nodes showed no signs of cancer before starting chemotherapy treatment.
  • People who have invasive breast cancer in both breasts.
  • People who are planned to receive hormone-based therapy before surgery (rather than chemotherapy).
  • People who have cancer that has spread to other parts of the body beyond the breast and nearby lymph nodes, including small numbers of distant spread (called oligometastatic disease).
  • People who have had invasive breast cancer in the past.
  • People who have, or have had, other types of cancer — with the exception of certain skin cancers (basal cell or squamous cell) or non-invasive cancer of the cervix or breast.
  • People who have already had surgery or radiation therapy to the armpit area before starting chemotherapy, including a procedure called sentinel lymph node biopsy.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 7 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Marjolein Smidt, MD, PhD, Maastricht University Medical Center

Phone: +31433881574

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
16 July 2020
Est. completion
1 July 2027

Where this trial is recruiting

🇳🇱 Netherlands

Primary endpoints

Disease free survival (DFS); Breast cancer specific survival (BCSS); Overall survival (OS); Axillary recurrence rate (ARR); Quality of life, as measured by EQ-5D-5L; Quality of life, as measured by Quality of Life Questionnaire Core 30 Items (QLQ-C30) and QLQ-BR23; Quality of life, as measured by BREAST-Q, which includes the following domains: satisfaction with breasts, psychosocial well being, physical well being, sexual well being.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 7 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov