Phase 3 Ovarian Cancer Trial, Recruiting NCT04575935 Sponsor: M.D. Anderson Cancer Center Condition: Ovarian Cancer
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Phase 3 Ovarian Cancer Trial, Recruiting

NCT04575935
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You are 18 years of age or older
  • You have been diagnosed with a specific type of advanced ovarian, peritoneal, or fallopian tube cancer (stage IIIC or IV, high-grade type), or a similar related cancer type (confirm with trial site)
  • Your doctor believes you are healthy enough to have surgery after completing 3 to 4 cycles of chemotherapy containing platinum, and scans show no cancer visible outside the abdomen
  • Your CA-125 blood marker levels (a cancer-related protein) have returned to a normal range after chemotherapy, OR your level is 500 or below and you are scheduled for a pre-surgery camera inspection of the abdomen to check if surgery is possible
  • Your surgery is planned to take place within 6 weeks of finishing your last chemotherapy cycle
  • You are reasonably active and able to care for yourself, with only minor limitations in daily activity (confirm with trial site what this means for your situation)
  • You are able to give signed consent and can attend follow-up appointments
  • You have a negative pregnancy test taken within 14 days before surgery
  • You have not had any other active cancer in the past five years, except certain common skin cancers (basal or squamous cell)

Who may not be able to join:

  • Your pre-surgery scans (CT, PET-CT, or MRI) show signs that the cancer cannot be safely removed using minimally invasive (keyhole) surgery, such as cancer affecting the small bowel, stomach, colon, rectum, diaphragm, spleen, liver, or certain other abdominal areas, or if fluid in the abdomen did not improve during chemotherapy
  • You have personal, family, psychological, or location-related circumstances that may make it hard to follow the study plan and attend follow-up visits
  • You are unable to safely tolerate being positioned with your head tilted downward for a period of time, or cannot tolerate the gas used to inflate the abdomen during keyhole surgery, as decided by your medical team
  • You have any other medical reason that makes keyhole surgery unsuitable for you, as assessed by your doctor

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Jose A Rauh-Hain, M.D. Anderson Cancer Center

Phone: 713-794-1759

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
5 August 2020
Est. completion
31 December 2028

Where this trial is recruiting

🇨🇦 Canada 🇮🇹 Italy 🇲🇽 Mexico 🇳🇱 Netherlands 🇺🇸 United States

Primary endpoints

Disease free survival (DFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov