Phase 2 Macular Degeneration Trial, Recruiting NCT04627428 Sponsor: Luxa Biotechnology, LLC Condition: Macular Degeneration
Back to Macular Degeneration

Phase 2 Macular Degeneration Trial, Recruiting

NCT04627428
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with dry age-related macular degeneration (a condition affecting vision in the back of the eye)
  • People who are able to understand what the trial involves and agree to take part
  • Adults aged over 55 years
  • People who are medically well enough to undergo a specific type of eye surgery involving an injection under the retina (the trial site will assess this using a standard health scoring scale)
  • Women who have been through menopause, or women who are the partner of a male participant who is unable to father children
  • Men who are willing to use barrier contraception (such as condoms) along with spermicide throughout the study

Who may not be able to join:

  • People who have a known allergy or sensitivity to eye-dilating drops or a dye called fluorescein (used in eye examinations)
  • People who have a serious ongoing medical condition that would make it difficult to take part in the study
  • People who currently have cancer or are receiving chemotherapy
  • People who have taken medication to suppress the immune system within the past six months
  • People with a history of certain infections, including toxoplasmosis, a fungal eye infection called retinal histoplasmosis, or tuberculosis
  • People who have taken part in another clinical trial and received an experimental treatment within the past six months
  • People who have any other medical condition that the trial doctor believes could interfere with the study, affect safety, or make the results harder to interpret (confirm with trial site)
  • Women who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Rajesh C Rao, M.D., University of Michigan Kellogg Eye Center

Phone: 05184371111

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Luxa Biotechnology, LLC
Registry
ClinicalTrials.gov
Start date
5 April 2022
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Safety and tolerability of RPESC-RPE-4W transplantation

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov