Glaucoma Trial, Recruiting NCT04635020 Sponsor: Helsinki University Central Hospital Condition: Glaucoma
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Glaucoma Trial, Recruiting

NCT04635020
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have given their signed consent to participate
  • People who have a clinically significant cataract (a cataract that is affecting vision or eye health)
  • People who are able to attend follow-up visits over a 12-month period
  • People who have mild to moderate exfoliation glaucoma, as defined by European Glaucoma Society guidelines
  • People whose glaucoma is either stable (eye pressure is within their personal target range) or unstable (eye pressure is above their personal target range), while using their current glaucoma medications
  • People whose target eye pressure is 16 mmHg or higher
  • People who are able to communicate in Finnish, Swedish, or English

Who may not be able to join:

  • People whose doctors have set a target eye pressure below 16 mmHg due to advanced glaucoma
  • People whose eye pressure before enrolment is 30 mmHg or higher and who are already using three or more glaucoma medications
  • People with a closed drainage angle in the eye
  • People with a condition where the eye's drainage angle did not develop normally
  • People with a significant corneal (front of the eye) disease or condition that could interfere with the trial
  • People who are unable to use eye drop medications
  • People whose central corneal thickness is less than 480 micrometres or more than 620 micrometres (a measurement taken during an eye exam)
  • People with certain active eye conditions, including uveitis, macular swelling, a specific type of age-related macular degeneration, advanced diabetic eye disease, eye tumours, a history of injections into the eye, or a displaced artificial lens (confirm with trial site)
  • People who have previously had eye surgery, laser vision correction surgery, or a procedure to reduce fluid production in the eye
  • People who have had two or more previous selective laser trabeculoplasty (SLT) or similar laser treatments to the eye's drainage system
  • People who are unable to participate due to another medical condition
  • People who are currently taking part in another clinical trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Mika Harju, MD, prof., Helsinki University Central Hospital

Phone: +358503608589

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Helsinki University Central Hospital
Registry
ClinicalTrials.gov
Start date
1 October 2020
Est. completion
1 September 2023

Where this trial is recruiting

🇫🇮 Finland

Primary endpoints

Group I: Change in the number of IOP lowering medications compared to baseline; Group II: Change in the IOP compared to baseline

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov