Phase 2 Ovarian Cancer Trial, Recruiting NCT04641247 Sponsor: GlaxoSmithKline Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT04641247
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are able to understand the study procedures and are willing to sign a written consent form agreeing to take part.
  • People who are able to follow the study schedule, including attending visits and following the treatment plan.
  • People who are currently taking niraparib (either alone or with another treatment) as part of a GlaxoSmithKline/TESARO-sponsored study that has already met its main research goals.
  • People whose treating doctor has assessed that they are currently benefiting from niraparib in their current study.
  • People who are capable of becoming pregnant and are sexually active, along with their partners, must agree to use an effective form of contraception throughout the study and for 180 days after the last dose of the study drug.

Who may not be able to join:

  • People who have already been permanently taken off niraparib in their current study, for any reason.
  • People who currently have unresolved side effects that have caused their niraparib treatment to be paused in their current study (joining may be possible once those side effects have resolved and treatment can resume — confirm with trial site).
  • People who are pregnant, or who plan to become pregnant during the study or within 180 days of the last dose of the study drug.
  • People who are breastfeeding, or who plan to breastfeed within 30 days of the final dose of the study drug (storing breast milk for use during this period is also not permitted).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: GSK Clinical Trials, GlaxoSmithKline

Phone: 877-379-3718

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Registry
ClinicalTrials.gov
Start date
16 April 2021
Est. completion
28 December 2026

Where this trial is recruiting

🇦🇹 Austria 🇨🇦 Canada 🇩🇰 Denmark 🇫🇷 France 🇮🇱 Israel 🇮🇹 Italy 🇪🇸 Spain 🇺🇸 United States

Primary endpoints

Number of participants with adverse events (AEs), serious adverse events (SAEs) and AEs of special interest (AESI); Number of participants with clinically significant changes in Eastern Co-operative Oncology Group (ECOG) performance status; Number of participants with clinically significant changes in hematology and clinical chemistry parameters; Number of participants with clinically significant changes in vital signs; Number of participants with clinically significant changes in physical examination; Number of participants with use of concomitant medications

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov