Phase 2 Parkinson's Disease Trial, Recruiting NCT04643327 Sponsor: The University of Queensland Condition: Parkinson's Disease
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Phase 2 Parkinson's Disease Trial, Recruiting

NCT04643327
Recruiting Phase 2 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with Parkinson's Disease and also have mild memory problems (a condition called mild cognitive impairment)
  • People who have been diagnosed with Parkinson's Disease but do not have memory problems
  • Healthy volunteers with no Parkinson's Disease diagnosis
  • All participants must be able to safely have an MRI scan

Who may not be able to join:

  • People who have been diagnosed with dementia
  • People for whom having an MRI scan is medically unsafe or not recommended
  • People who have bipolar disorder, schizophrenia, or a history of alcohol or substance misuse
  • People who have major depression
  • People who have had thoughts of suicide
  • People who may have difficulty following the requirements of the study
  • People who have a significant brain or nervous system condition other than Parkinson's Disease
  • People who have vascular dementia (a type of dementia caused by reduced blood flow to the brain)
  • People who have a known sensitivity or allergic reaction to a medication called levetiracetam
  • People who are currently taking anti-seizure (anticonvulsant) medications
  • People who are currently taking other medications that are excluded by the trial (confirm with trial site for the specific list)
  • People who have severely reduced kidney function
  • People who have significantly abnormal vitamin B12 levels or thyroid function test results, outside the normal range for older adults
  • Women who are of childbearing age and could potentially become pregnant

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 9 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Australian sites

University of Queensland Centre for Clinical Research, Brisbane, Queensland
0733465028

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
The University of Queensland
Registry
ClinicalTrials.gov
Start date
9 February 2021
Est. completion
1 January 2025

Where this trial is recruiting

🇦🇺 Australia

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Pattern separation performance (behavioural outcome); Hippocampal DG/CA3 subfield activity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov