Phase 3 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults aged 18 to 80 years old
- People who have had a blockage in a large artery supplying the front part of the brain (confirmed by a special type of brain scan called a CTA or MRA)
- People whose stroke symptoms started less than 24 hours before the brain scan was taken
- People whose brain scans show a specific pattern where the area of dead brain tissue is small compared to the area of brain tissue at risk — measured using specialised imaging software (confirm with trial site for exact scan requirements)
- People who were largely independent before their stroke, with little to no disability beforehand
- People with a stroke severity score of 6 or higher on a standard medical scale (NIHSS), indicating at least a moderate stroke
Who may not be able to join:
- People for whom the standard mechanical clot removal procedure (thrombectomy) is not suitable
- People over 80 years old who have more than 10 small areas of old bleeding visible on a pre-treatment brain MRI
- People who were already significantly dependent or disabled before the stroke
- People with a known blockage in both the neck and brain arteries that would require a stent to treat
- People whose brain scans show a large area of already damaged brain tissue (below a specific score on a standard imaging scale)
- People with a known allergy to the study drug (cangrelor) or any of its ingredients, including mannitol or sorbitol
- People with a history of bleeding inside the brain
- People showing signs of active bleeding or a broken bone from a recent injury at the time of examination
- People who have recently had surgery that carries a significant risk of bleeding
- People taking a blood-thinning medication called a VKA (such as warfarin) with a blood test result showing it is too active (INR above 1.7)
- People who have taken certain blood-thinning medications (heparin or direct oral anticoagulants) in the past 48 hours, where blood test results show the medication is still significantly active in the body
- People with a low platelet count (below 100,000 per mm³), meaning the blood may not clot properly
- Women of childbearing age who have not had a pregnancy test, or who have tested positive for pregnancy
- People who are under a legal protection order (confirm with trial site)
- People who are not covered by a national health insurance scheme
- People who have not given their consent to participate — or, in urgent situations, whose nominated trusted person has objected on their behalf
- People already taking part in another stroke treatment study that could interfere with this trial
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 01 48 03 65 65
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Favorable functional evaluation at 3 month for patients with acute ischemic strocke treated by cangrelor.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.