Breast Cancer Trial, Recruiting NCT04669873 Sponsor: Instituto Brasileiro de Controle do Cancer Condition: Breast Cancer
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Breast Cancer Trial, Recruiting

NCT04669873
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Women aged 50 years or older
  • People who have had breast-conserving surgery (surgery that removes the tumour but keeps most of the breast)
  • People whose tumour measured less than 3 cm under the microscope (invasive part only)
  • People diagnosed with a type of breast cancer called invasive adenocarcinoma (not the classic form of invasive lobular carcinoma)
  • People whose cancer was found in only one spot in the breast (not spread to multiple areas)
  • People whose cancer is graded as Grade 1 or Grade 2 (lower-grade tumours that tend to grow more slowly)
  • People who are generally well and able to carry out daily activities with little or no limitation (confirmed by a standard health scale called ECOG 0–1)
  • People whose cancer has not spread into nearby blood vessels or lymph vessels
  • People whose underarm (axillary) lymph nodes tested negative for cancer
  • People whose surgery left at least 2mm of healthy tissue around the tumour (with some exceptions for the deepest surgical edge)
  • People who have not previously had radiotherapy to the breast or the chest area between the lungs (mediastinum)
  • People whose cancer has not spread to other parts of the body through the bloodstream

Who may not be able to join:

  • People who have had a previous cancer diagnosis, other than certain common skin cancers (non-melanoma skin cancer)
  • People who have had a full breast removal (mastectomy) rather than breast-conserving surgery
  • People diagnosed with the classic type of invasive lobular carcinoma
  • People who received chemotherapy before their surgery (neoadjuvant chemotherapy)
  • People whose breast cancer tests positive for a protein called HER2 (HER2+)
  • People diagnosed with triple-negative breast cancer
  • People whose cancer involves lymph vessels in a way classified as intravascular lymphoma
  • People who have a medical reason that would make radiotherapy unsafe for them (confirm with trial site)
  • People who would have difficulty attending follow-up appointments due to where they live, their personal circumstances, or their mental health

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Phone: +551198639-1945

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Instituto Brasileiro de Controle do Cancer
Registry
ClinicalTrials.gov
Start date
4 March 2021
Est. completion
7 December 2025

Where this trial is recruiting

🇧🇷 Brazil

Primary endpoints

Rate of local recurrence

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov