Phase 2 Breast Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are a man or woman who has been diagnosed with invasive breast cancer, confirmed through a tissue biopsy.
- Your breast cancer has been tested and confirmed as "triple negative," meaning it tests negative (or very low) for estrogen receptors, progesterone receptors, and HER2 protein.
- You are planning to receive chemotherapy before surgery to treat your breast cancer, or you started that chemotherapy no more than 2 weeks ago.
- You are reasonably able to carry out daily activities (your doctor has rated your general health and functioning as acceptable for this trial).
- You are 18 years of age or older.
- If you are someone who could become pregnant, you agree to use reliable birth control (such as hormonal methods, barrier methods, or abstinence) throughout the study, and you agree to tell your doctor right away if you become pregnant.
- You are able to understand what the study involves and are willing to sign a consent form agreeing to take part.
Who may not be able to join:
- You have had kidney stones within the past year.
- You have a condition called sarcoidosis (a disease involving inflammation in body tissues).
- Your blood calcium level was too high within the 30 days before starting chemotherapy (confirm with trial site).
- You have had an allergic reaction to vitamin D or a similar substance in the past.
- You are currently pregnant, as the effects of high-dose vitamin D on an unborn baby are not fully known.
- You are currently breastfeeding, as there may be unknown risks to the baby from high-dose vitamin D.
- You have already received any treatment for this breast cancer, including surgery, radiation, chemotherapy, hormone therapy, or any experimental treatment, before joining the study.
- You are already taking vitamin D at a dose of 50,000 International Units (IU) once per week.
⚠️ Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Emily H Douglas, MD, Wake Forest University Health Sciences
Phone: 336-713-0031
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Number of Pathologic Complete Response (pCR) in Vitamin D Supplementation Group
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.