Phase 2 Ovarian Cancer Trial, Recruiting NCT04686682 Sponsor: Jacobio Pharmaceuticals Co., Ltd. Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT04686682
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older at the time of signing the consent form
  • People whose general health and ability to carry out daily activities is rated as fully active or restricted only in physically strenuous activity (this is measured using a standard oncology scoring scale called ECOG, with a score of 0 or 1)
  • People who have been confirmed through laboratory testing to have an advanced solid tumour cancer that has continued to grow despite standard treatments, where standard treatments could not be tolerated, or where no standard treatment exists
  • People who have a type of blood cancer called acute myeloid leukaemia (AML) that has come back or has not responded to treatment, as defined by specific medical guidelines (WHO 2016)
  • People with a life expectancy of at least 3 months
  • People with a solid tumour who have at least one tumour that can be measured using standard imaging criteria (confirm with trial site)
  • People whose liver, kidneys, and other organs are functioning at a sufficient baseline level (confirm with trial site)

Who may not be able to join:

  • People who have been diagnosed with a different type of cancer within the last 3 years
  • People with a known serious allergy to the study drug or its ingredients
  • People with cancer that has actively spread to the brain or spinal cord
  • People with a history of inflammation around the heart or a significant fluid build-up around the heart
  • People with a history of a lung condition called interstitial lung disease
  • People who have had a significant active infection within the past 2 weeks
  • People known to have HIV infection
  • People who test positive for hepatitis B virus
  • People who test positive for hepatitis C virus, or whose hepatitis C virus levels in the blood are undetectable (confirm with trial site)
  • People with severe or uncontrolled other medical conditions
  • People with a history of heart attack, unstable chest pain (angina), heart bypass surgery, or stroke
  • People with significantly impaired heart function or serious heart disease
  • People with an abnormal heart electrical reading (specifically, a QTcF measurement above 470 milliseconds) at the screening stage
  • People with a history of significant blood clots or serious bleeding disorders
  • People who still have side effects from previous treatments that are rated above a mild level (Grade greater than 1)
  • People with a history of a blocked bile duct caused by cancer
  • People who are pregnant or breastfeeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Jacobio Pharmaceuticals, Jacobio Pharmaceuticals

Phone: 86 10 56315466

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Jacobio Pharmaceuticals Co., Ltd.
Registry
ClinicalTrials.gov
Start date
7 May 2021
Est. completion
1 January 2028

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Number of participants with dose limiting toxicities

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov