Peripheral Arterial Disease Trial, Recruiting NCT04687215 Sponsor: University of Chicago Condition: Peripheral Arterial Disease
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Peripheral Arterial Disease Trial, Recruiting

NCT04687215
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have had Type 2 diabetes for more than 1 year
  • People whose diabetes is classified as stage 3 or lower (confirm with trial site)
  • People who are 18 years of age or older
  • People who have ongoing, hard-to-treat nerve pain in their legs or feet related to diabetes, which has not responded well to treatment
  • People whose ankle-brachial index (a test that compares blood pressure in the ankle and arm to check blood flow) result is below 0.9 (confirm with trial site)

Who may not be able to join:

  • People who are currently taking blood-thinning medications (anticoagulants)
  • People who currently have an active infection
  • People whose HbA1c level (a measure of long-term blood sugar control) is above 10 (confirm with trial site)
  • People who have a diagnosed psychiatric disorder or problems with memory or thinking
  • People who currently use illegal drugs
  • People who are currently receiving dialysis (a treatment that filters the blood when the kidneys cannot)
  • People with a Body Mass Index (BMI) above 35
  • People who have had surgery within the last 30 days
  • People who have an open sore or ulcer on their legs or feet
  • People who have calcium build-up in the arteries of their legs (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Magdalena Anitescu, MD, PhD, University of Chicago

Phone: (773) 834-5234

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
27 January 2022
Est. completion
1 August 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Improve vascular changes; Vascular improvement on lower extremities with the Ankle Brachial Index (ABI); Vascular improvement on lower extremities with the Toe Brachial Index (TBI); Vascular improvement on lower extremities with the Doppler Flowmetry

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov