Motor Neurone Disease Trial, Recruiting NCT04715399 Sponsor: University of Pennsylvania Condition: Motor Neurone Disease
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Motor Neurone Disease Trial, Recruiting

NCT04715399
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with a brain or nervous system condition such as Alzheimer's disease, Parkinson's disease, ALS (Lou Gehrig's disease), or a related condition
  • People who have a family history of certain inherited brain or nervous system diseases (such as familial FTD or familial ALS), whether or not they currently have symptoms or carry a related gene
  • People who have no known brain or nervous system disease and are willing to provide comparison data for the study

Who may not be able to join:

  • Anyone who is under 18 years of age
  • Anyone whose other health conditions (such as heart problems, a history of brain surgery, infections, or psychological conditions) might affect the study results or make participation difficult (confirm with trial site)
  • People with certain metal implants that are not safe for MRI scans may not be able to take part in the imaging portion of the study
  • People taking blood-thinning medications may not be able to take part in the spinal fluid collection portion of the study
  • Women who are currently pregnant (if a participant becomes pregnant during the study, certain research activities will be paused until after the pregnancy)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: David Irwin, MD, University of Pennsylvania

Phone: 215-746-2781

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
29 May 2020
Est. completion
30 May 2070

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Status of progression - changes in neuropsychological tests.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov