Crohn's Disease and Colitis Trial, Recruiting NCT04740541 Sponsor: The Hospital for Sick Children Condition: Crohn's Disease and Colitis
Back to Crohns Disease And Colitis

Crohn's Disease and Colitis Trial, Recruiting

NCT04740541
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Men between 18 and 49 years old
  • People who have given written agreement to take part (or whose legal representative has done so)
  • People with confirmed inflammation in the small intestine (ileum) and/or colon, whose disease is currently relatively stable and scores 8 or below on a standard disease activity measure called the Harvey-Bradshaw Index
  • People who have shown some signs of active disease, such as a history of elevated levels of a blood marker called CRP, or signs of active inflammation in the gut lining
  • People with no blockages or narrowings in the intestine that would make it difficult to eat a normal diet
  • People whose weight has been stable for at least 3 months and who are not receiving nutrition through a feeding tube
  • People who are willing to complete screening steps (including height, weight, a fasting blood test, and a medical history questionnaire) and willing to eat the diet provided by the trial

Who may not be able to join:

  • People whose inflammation is not well controlled and who are likely to need surgery or a change in treatment within the next 4 weeks
  • People currently taking corticosteroids at a dose greater than 20 mg per day
  • People who show no signs of active inflammation
  • People taking medications known to affect how the body processes protein and amino acids (such as steroids)
  • People who have recently experienced significant weight loss
  • People currently following a weight-loss diet
  • People who are unlikely to be able to tolerate the study diet
  • People who are not expected to be able to follow the study procedures
  • People who drink more than 2 cups of coffee per day
  • People who drink more than one alcoholic drink per day

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Glenda Courtney-Martin, PhD, RD, The Hospital for Sick Children

Phone: 4168137454

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
The Hospital for Sick Children
Registry
ClinicalTrials.gov
Start date
2 February 2024
Est. completion
30 August 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Requirement of Threonine in Adult Males with Crohn's Disease

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov