Early Phase 1 Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Healthy volunteers:

• Adults between 18 and 75 years of age who do not have a physical disability or health condition that would prevent them from completing physical tasks in the study
• People who are proficient in English, as the study requires following spoken instructions during sessions
• People who are able to understand the study's goals and procedures and can give their informed consent to take part
• People who are able to visit the study centre up to 5 times per week, for sessions of up to 4 hours, for a period of at least 2 months and up to 1 year

People who have had a stroke or spinal cord injury:

• Adults between 18 and 75 years of age who have limited use of at least one hand as a result of a stroke or spinal cord injury
• People who are at least 6 months past their stroke, or at least 1 year past their spinal cord injury
• People who are proficient in English, as the study requires following spoken instructions during sessions
• People who are able to understand the study's goals and procedures and can give their informed consent to take part
• People who are able to visit the study centre up to 5 times per week, for sessions of up to 4 hours, for a period of at least 2 months and up to 1 year

People who have had a brain or nerve injury:

• Adults between 18 and 75 years of age who have limited or no use of at least one limb due to a brain or nerve injury — such as a traumatic brain injury, brachial plexus injury, peripheral nerve damage, or Parkinson's Disease
• People who are proficient in English, as the study requires following spoken instructions during sessions
• People who are able to understand the study's goals and procedures and can give their informed consent to take part
• People who are able to visit the study centre up to 5 times per week, for sessions of up to 4 hours, for a period of at least 2 months and up to 1 year

Who may not be able to join:

• People who are currently taking part in another study that could affect this study's procedures or results
• People who have severe pressure sores (Stage III–IV) that would interfere with their involvement in the study, such as sores on the limb being studied or that prevent sitting for extended periods
• People with a history of epilepsy
• People who have a permanently implanted electronic medical device, such as a deep brain stimulator, heart pacemaker, spinal stimulator, or vagus nerve stimulator
• People who have physical differences in their arms, hands, legs, feet, or spine that would prevent electrical stimulation from being applied safely
• People who rely on a ventilator to breathe
• People with a history of serious mood or thought disorders
• People with uncontrolled autonomic dysreflexia (a condition involving sudden changes in the nervous system — confirm with trial site)
• People with severe muscle stiffness or spasms in the limb being studied that cannot be managed with medication or that prevents electrical stimulation
• People who have received Botulinum toxin (e.g. Botox) injections in the limb being studied within the past 3 months
• People who have active cancer at or near the area where electrical stimulation would be applied
• People with a history of heart or kidney disease
• People with a history of additional neurological conditions, such as multiple sclerosis or multiple strokes
• People with other serious health conditions that could affect their ability to participate, such as uncontrolled high blood pressure, uncontrolled diabetes, rheumatic disease, peripheral neuropathy, or HIV/AIDS
• People with a substance abuse problem, including alcohol
• People who are pregnant
• People who are currently imprisoned

Important: Always verify eligibility with the trial site directly before applying.