Phase 2 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who have had an ischemic stroke (caused by a blockage) affecting the front part of one side of the brain
- People who are 18 years of age or older
- People who are at least 5 days past their stroke but no more than 8 weeks past their stroke when treatment starts
- People who have weakness on one side of the body (arm and/or leg) that requires inpatient rehabilitation
- People who have someone available to help with daily rehabilitation practice and transportation when needed
- People who have enough language ability to understand the consent forms and follow daily therapy instructions
- People who have at least some movement in the shoulder or fingers, OR some visible movement in the hip
Who may not be able to join:
- People who had a significant disability or difficulty with daily activities before the stroke
- People who do not have sufficient resources or whose health would prevent them from eventually returning to living outside of a care facility
- People with a history of dementia
- People with a history of hepatitis, or liver problems shown by abnormal liver test results
- People with a history of kidney problems or poor kidney function based on blood test results
- People with cancer or another serious ongoing illness that makes surviving one year unlikely, or that would interfere with exercise and skill practice
- People who had a significant disabling condition before the stroke (for example, Parkinson's disease, severe brain injury, or amputation)
- People who had a seizure related to their stroke
- People with a current or past diagnosis of epilepsy
- People currently taking any of the following seizure medications: Carbamazepine, Phenobarbital, or Phenytoin
- People who are pregnant, breastfeeding, or who test positive for pregnancy at the start of the trial
- Women who could become pregnant and are not using at least one highly effective form of birth control, or two forms of effective birth control
- People who are known to be HIV positive
- People currently taking any of the following antifungal or antibiotic medications: Ketoconazole, Itraconazole, Voriconazole, Rifampin, Clarithromycin, or Rifabutin combined with a Protease Inhibitor
- People currently taking the herbal supplement St. John's Wort
- People currently taking Paxlovid
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Sean Dukelow, MD PhD FRCPC, University of Calgary
Phone: 403-944-4050
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Change in Fugl-Meyer Upper Extremity Assessment Score; Change in 10-Meter Walk Test Score
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.