Ovarian Cancer Trial, Recruiting NCT04794322 Sponsor: Massachusetts General Hospital Condition: Ovarian Cancer
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Ovarian Cancer Trial, Recruiting

NCT04794322
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You still have your uterus and have not had uterine ablation, tubal ligation, or both fallopian tubes removed
  • Group 1: Women who are scheduled for surgery or a keyhole diagnostic procedure because doctors suspect (but have not yet confirmed) ovarian or fallopian tube cancer
  • Group 2: Women who are known carriers of a BRCA1 or BRCA2 gene mutation and are scheduled for surgery to remove their ovaries and fallopian tubes as a preventive measure

Who may not be able to join:

  • You have already received a confirmed cancer diagnosis from a recent tissue or cell sample test
  • You are unable to give informed consent to take part in the study
  • You are under 30 years of age
  • Doctors are unable to collect the minimum required amount of blood from you
  • Doctors are unable to collect the minimum required amount of uterine lavage (a fluid sample from the womb) from you
  • Having blood drawn would put you at risk, for example if you have a bleeding disorder like haemophilia or severe anaemia
  • You have a previous history of ovarian or womb (endometrial) cancer
  • You have been treated within the last year for a cancer that had spread from where it originally started (hormonal therapy does not count)
  • You have a history of untreated severe cervical cell changes (CIN3)
  • You have a history of treated severe cervical cell changes (CIN3) and had an abnormal cervical smear test in the past year (confirm with trial site for details on pre-surgery smear testing)
  • You are currently pregnant
  • You have a known inherited condition called Lynch syndrome

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Christos Patriotis, PhD, National Cancer Institute (NCI)

Phone: 206 667 3438

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
13 April 2020
Est. completion
31 August 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Genomic biomarkers assessing mutations and methylation of tumor DNA, and protein biomarkers measured as the concentration of a protein in pg/mL, both types of biomarkers measured in the collected biospecimens.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov