COPD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People between 40 and 75 years of age.
• People whose condition is stable and who are taking less than 10mg of prednisone (or a similar steroid medication) per day.
• People who have not smoked for at least 4 months before the screening visit and who are willing to remain non-smoking for the entire study period.
• People who completed a supervised lung rehabilitation program within the past 12 months, or who are regularly continuing maintenance lung rehabilitation if their original program was completed more than 12 months ago.
• People who have a current, up-to-date pneumococcal vaccination.
• People who have a current, up-to-date influenza (flu) vaccination.
• People who are willing and able to attend all required follow-up visits and complete all study procedures.

Who may not be able to join:

• People whose lung scan results show a specific structural lung characteristic (very high fissure completion on a chest CT scan), or whose airflow test shows no collateral ventilation (confirm with trial site).
• People who produce more than about 4 tablespoons of mucus per day.
• People who have had a heart attack within the 6 months before screening.
• People with uncontrolled heart failure.
• People who have had three or more episodes of pneumonia in the past year.
• People who have had three or more severe COPD flare-ups in the past year.
• People who have previously had a lung transplant, lung volume reduction surgery, or surgical removal of part or all of a lung.
• People with a significant lung condition involving abnormally widened airways (bronchiectasis).
• People who cannot safely stop taking blood thinners or anti-clotting medications for 7 days.
• People with uncontrolled high blood pressure in the lungs, or a history of a related heart condition called Cor Pulmonale, based on a heart ultrasound done within the past 3 months.
• People whose heart pumping function is below a certain level (less than 40%), based on a heart ultrasound done within the past 3 months.
• People with a resting heart rate that is too slow, or with certain types of irregular heartbeats (confirm with trial site for specific heart rhythm details).
• People whose lung airflow measurement (after using a bronchodilator) falls outside a specific range — either too low or too high — compared to what is expected for someone their age and size.
• People whose total lung capacity is below what would normally be expected for someone their age and size, as measured by a breathing test.
• People whose lung air trapping levels fall below certain thresholds, depending on their type of emphysema, as measured by a breathing test.
• People whose lungs' ability to transfer oxygen into the blood is below 20% of the expected level.
• People whose walking distance in a 6-minute walk test (done after rehabilitation) is either less than 100 metres or more than 450 metres.
• People with too much carbon dioxide in their blood while breathing normal room air.
• People with too little oxygen in their blood while breathing normal room air.

Important: Always verify eligibility with the trial site directly before applying.