Phase 1 Ovarian Cancer Trial, Recruiting NCT04811703 Sponsor: Hospices Civils de Lyon Condition: Ovarian Cancer
Back to Ovarian Cancer

Phase 1 Ovarian Cancer Trial, Recruiting

NCT04811703
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 18 and 75 years old
  • People with a general health status that allows them to carry out daily activities, either fully or with some limitations (confirm with trial site what level of functioning is required)
  • People who have been diagnosed with a specific type of cancer — confirmed by lab testing — that started in the ovaries, fallopian tubes, or the lining of the abdomen, at a certain stage of advancement, and who have had some response (but not enough) to three cycles of a standard chemotherapy combination, meaning full surgical removal of the tumour is not yet possible
  • People whose blood cell counts meet certain minimum levels — enough white blood cells, red blood cells, and platelets — as confirmed by blood tests
  • People whose kidneys and liver are functioning well enough, as confirmed by blood tests
  • People who do not have serious unstable health conditions, such as a recent heart attack, uncontrolled blood pressure, or severe infections, among others (confirm with trial site for the full list)
  • People who have given written agreement to take part before any trial procedures begin
  • People who are covered by a national health insurance system

Who may not be able to join:

  • People whose cancer has spread to areas outside the abdomen in a way that would prevent potentially curative surgery
  • People who have signs of bowel blockage, bowel lesions at risk of tearing, or inflammatory bowel disease
  • People who cannot receive intravenous carboplatin-paclitaxel chemotherapy, including those with a known severe allergic reaction to paclitaxel
  • People who cannot undergo the PIPAC procedure (a type of treatment delivered directly into the abdomen), including those with a known allergy to cisplatin or similar drugs, doxorubicin or similar drugs, or those with certain heart conditions
  • People with a known allergy to sodium thiosulfate, sulfites, or related substances
  • People who have received a live vaccine within 3 months before the start of the trial, or who plan to receive one during the trial
  • People who are pregnant or breastfeeding
  • People who are under legal guardianship or any form of legal protection, or who have had their liberty restricted
  • People who are currently participating in another clinical trial that has an overlapping exclusion period, or one that could affect the results of this study
  • People who, for geographical, personal, or psychological reasons, would be unable to attend the required follow-up visits

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Justine ARQUILLIERE, MD, Hospices Civils de Lyon

Phone: 04 78 86 23 71

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Registry
ClinicalTrials.gov
Start date
30 July 2021
Est. completion
1 June 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Dose-limiting toxicities

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov