Lymphoma Trial, Recruiting NCT04824950 Sponsor: Centre Henri Becquerel Condition: Lymphoma
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Lymphoma Trial, Recruiting

NCT04824950
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 or older
  • People newly diagnosed with a specific type of blood cancer called primary mediastinal large B-cell lymphoma, confirmed by a tissue biopsy analysed according to standard international guidelines (WHO 2016 classification)
  • People at any stage of this condition (stages I through IV)
  • People with any IPI score (a scoring system used to assess lymphoma severity), from 0 to 5
  • People whose cancer involves the area in the middle of the chest (the mediastinum)
  • People who have not yet received treatment, except for a short course of steroid medication (below a certain dose, for no more than 7 days) given in an emergency situation
  • People whose treating team plans to start a specific chemotherapy regimen (R-CHOP-14 or R-ACVBP) guided by a type of imaging scan called PET-CT
  • People whose pre-treatment PET-CT scan shows tumour activity above a certain level (a Deauville score of 4 or higher)
  • People who have signed the informed consent form before any study procedures begin
  • People who are covered by a social protection or health insurance plan

Who may not be able to join:

  • People who have already started chemotherapy
  • People for whom the FDG PET-CT scan (a type of nuclear imaging) is not medically suitable
  • People whose cancer does not involve the chest (mediastinal) area
  • People with a positive HIV test result
  • People with active hepatitis B or C (positive test result combined with detectable levels of the virus)
  • Adults who are under legal guardianship or a similar protective legal arrangement
  • People who are pregnant or currently breastfeeding
  • People who, for any reason, are unable to understand the study or follow its requirements (for example, due to language barriers, psychological difficulties, or geographical limitations)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: VINCENT CAMUS, MD, Centre Henri Becquerel

Phone: +33232082497

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Centre Henri Becquerel
Registry
ClinicalTrials.gov
Start date
22 March 2021
Est. completion
1 March 2028

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Correlation between circulating tumoral DNA detection and complete molecular response

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov