Eczema Trial, Recruiting NCT04864886 Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Condition: Eczema
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Eczema Trial, Recruiting

NCT04864886
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a confirmed genetic diagnosis of a primary immune deficiency (a condition where the immune system does not work properly due to a gene change)
  • People who have a gene change that may affect immune function, or who have a history of infections that are unusually frequent, long-lasting, or severe compared to what is typical
  • People who have been diagnosed by a doctor with psoriasis (a skin condition causing scaly, inflamed patches)
  • People who have been diagnosed by a doctor with atopic dermatitis (a chronic itchy skin condition, also known as eczema)
  • Healthy volunteers who have no known immune deficiency, psoriasis, or eczema
  • People aged 18 to 75 years
  • People who are willing to allow their blood, tissue biopsy, and other collected samples to be stored for future research
  • People who are able to give their own informed consent to take part

Who may not be able to join:

  • People who are currently taking, or have taken in the past 3 months, blood-thinning or anti-clotting medications (not including aspirin or common anti-inflammatory pain relievers such as ibuprofen)
  • People who are currently taking, or have taken in the past 3 months, medications that affect the immune system (such as chemotherapy or steroids), unless the lead researcher has specifically approved this
  • People who have a history of forming keloid scars (thick, raised scar tissue that grows beyond the original wound)
  • People who are currently pregnant, breastfeeding, or lactating
  • People who have any other condition that the investigator believes would make participation unsuitable (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ian A Myles, M.D., National Institute of Allergy and Infectious Diseases (NIAID)

Phone: (301) 605-2896

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
10 August 2021
Est. completion
30 June 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in relative abundance of microbial skin taxa and/or skin metabolites associated with wound healing or immune mediated disorders.; Fold difference in metabolic pathways associated with immune pathways.; Fold differences in metabolic pathways related to wound healing.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov