Oesophageal Cancer Trial, Recruiting NCT04867590 Sponsor: University Hospital, Angers Condition: Oesophageal Cancer
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Oesophageal Cancer Trial, Recruiting

NCT04867590
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults who have a condition called Barrett's oesophagus, where the lining of the food pipe has changed, measuring between 2 cm and 6 cm in length
  • People whose Barrett's oesophagus has been confirmed by a tissue sample (biopsy) to have low to high grade cell changes (dysplasia), or who have had a very early, non-spreading cancer of the food pipe that has already been surgically removed
  • People who have signed the consent form to take part in the study (note: signing consent can happen before the biopsy results are fully confirmed)

Who may not be able to join:

  • People over 85 years of age
  • Women who are pregnant, breastfeeding, or in labour
  • People who are in detention by a court or government decision
  • People receiving psychiatric treatment against their will
  • People who are under a legal protection order
  • People who are not able to give their own consent to participate
  • People who do not understand French or are unable to read
  • People who are not enrolled in or covered by a French social security scheme
  • People who have active inflammation of the food pipe caused by stomach acid, radiation, or related complications at the time of treatment
  • People who have a visible lesion in the food pipe that biopsies have confirmed to be cancer
  • People who previously had a food pipe cancer removed by an endoscopic procedure where the cancer reached the edges of the removed tissue, or where the cancer was poorly formed or had spread more than 500 micrometres into the tissue layer beneath the surface lining (confirm with trial site)
  • People who have previously had any ablation (tissue removal or destruction) treatment or a stretching procedure for a narrowed food pipe
  • People with a significantly narrowed food pipe that cannot be passed through with a standard medical camera scope
  • People with enlarged veins in the food pipe (varices) or high blood pressure in the liver's blood vessels (portal hypertension)
  • People taking blood-thinning medications that cannot be safely stopped before the procedure (low-dose aspirin up to 100 mg per day on its own may be acceptable — confirm with trial site), or people with uncorrectable bleeding or clotting problems
  • People for whom anaesthesia is medically not suitable
  • People who are unable to take a type of stomach acid-reducing medication called proton pump inhibitors (PPIs) by mouth

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Elodie CESBRON-METIVIER, Ph.D., UH Angers

Phone: +33241353148

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
University Hospital, Angers
Registry
ClinicalTrials.gov
Start date
25 March 2022
Est. completion
25 July 2031

Where this trial is recruiting

🇫🇷 France

Primary endpoints

The rate of full eradication of Barrett esophagus (metaplasia), which is defined by the absence of residual Barrett esophagus in the check-up endocopy after 3 months

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov