Stroke Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Stroke patients may be eligible if they:

• Are under 80 years old
• Score above 24 on a standard memory and thinking test (Mini Mental State Examination)
• Have a moderate level of disability — able to do some things independently but with some limitations (Modified Rankin Scale score of 1–3)
• Have a stroke that affected only one side of the brain
• Had their stroke more than 6 months ago and their condition has been stable since then
• Have walking difficulties, such as reduced speed or increased tiredness when walking
• Are able to walk without braces or walking aids, but walk with an abnormal pattern, and have only mild muscle stiffness (Ashworth score below 2)

Parkinson's disease patients may be eligible if they:

• Are under 80 years old
• Score above 24 on a standard memory and thinking test
• Score below 28 on a standard Parkinson's disease movement assessment (UPDRS Part III)
• Have a stable condition and stable medication
• Have an abnormal walking pattern
• Are able to walk without braces or walking aids, but walk with an abnormal pattern

Multiple sclerosis patients may be eligible if they:

• Are under 60 years old
• Score above 24 on a standard memory and thinking test
• Have a disability level score between 3 and 5 on a standard MS disability scale (EDSS)
• Have had a stable condition with no relapses or worsening in the last 6 months
• Have an abnormal walking pattern, such as unsteadiness, slowing down, or mild muscle stiffness (Ashworth score below 2)
• Are able to walk without braces or walking aids

Who may not be able to join:

Stroke patients may not be eligible if they:

• Have had strokes affecting more than one area, or both sides of the brain
• Have a condition called "neglect," where one side of space or the body is ignored (confirm with trial site)
• Have a foot and ankle condition called equinism, where the foot is fixed in a downward position (confirm with trial site)
• Have significant muscle stiffness (Ashworth score of 2 or above)
• Have a tight, non-flexible Achilles tendon (the tendon at the back of the ankle)
• Have received neurotoxin injections (such as Botox) in the 3 months before the study
• Have had a muscle-relaxing medication called Baclofen started or changed in the week before the study begins
• Have another condition that significantly affects the use of their legs
• Have received a rehabilitation treatment involving music in the year before the study

Parkinson's disease patients may not be eligible if they:

• Have another condition that significantly affects the use of their legs
• Have any changes made to their Parkinson's medications during the study
• Have received a rehabilitation treatment involving music in the year before the study

Multiple sclerosis patients may not be eligible if they:

• Have another condition that significantly affects the use of their legs
• Have received neurotoxin injections (such as Botox) in the 3 months before the study
• Have had a muscle-relaxing medication called Baclofen started or changed in the week before the study begins
• Have significant muscle stiffness (Ashworth score of 2 or above)
• Have a tight, non-flexible Achilles tendon (the tendon at the back of the ankle)
• Have received a rehabilitation treatment involving music in the year before the study

Important: Always verify eligibility with the trial site directly before applying.