Phase 2 Stroke Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- A person who has given written agreement to take part (or whose legal representative has done so) before any study procedures begin.
- People aged between 18 and 80 years old at the time of signing the consent form.
- People who were admitted to hospital within 48 hours of their stroke symptoms starting.
- People who have been diagnosed with their first-ever ischemic stroke (a stroke caused by a blocked blood vessel, not bleeding).
- People whose stroke has caused a certain level of measurable impairment, based on a standard stroke severity scoring tool (confirm with trial site).
- People who have been diagnosed with sleep apnea of at least a moderate level of severity, based on a standard breathing measurement (confirm with trial site).
Who may not be able to join:
- People who have a specific type of sleep apnea related to the brain (central sleep apnea) combined with reduced heart pumping function (confirm with trial site).
- People who were already using a breathing machine or device for sleep apnea before their stroke.
- People who are considered at risk of inhaling food or fluid into their lungs.
- People who have a feeding tube inserted through the nose and into the stomach.
- People whose stroke was temporary (a TIA or "mini-stroke"), involved bleeding in the brain, or involved bleeding around the brain.
- People whose stroke was caused by an underlying condition such as an abnormal blood vessel, blood vessel inflammation, a brain tumour, a head injury, or a tendency to bleed.
- People who are in cardiorespiratory distress (serious breathing or heart difficulties).
- People with a severe long-term lung condition that requires them to use supplemental oxygen.
- People who have another condition affecting the brain or nervous system, such as dementia or multiple sclerosis.
- People with uncontrolled psychosis or severe agitation.
- People whose level of consciousness falls below a certain threshold on a standard assessment scale (confirm with trial site).
- People with certain conditions affecting awareness or understanding of language (confirm with trial site).
- People who do not have enough arm and hand function to manage a breathing mask and do not have a carer available overnight to assist.
- People who are unable to take part in the hospital's rehabilitation program.
- People who are pregnant or breastfeeding.
- People who are already taking part in another clinical trial (participation in a standard-of-care registry may be acceptable — confirm with trial site).
- People who, in the opinion of the trial investigator, are unsuitable for breathing support treatment for any other reason.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Sílvia Correia, MD, Trofa Saúde Hospital
Phone: 00351969043466
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Proportion of patients with improvement in neurological parameters (reduction of ≥1 point from the beginning in Rankin scale) 1 month after stroke.
Can't join this trial?
Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.