Phase 3 Pancreatitis Trial, Recruiting

Written by an AI model from the ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are 18 years of age or older
• You have been admitted to hospital with acute pancreatitis, meaning you have at least 2 of these: typical pancreatitis pain, blood enzyme levels (amylase and/or lipase) more than 3 times the normal limit, or a scan showing signs of acute pancreatitis
• You have gallstones that have been detected by any type of scan or imaging
• You are willing and able to give your informed consent to take part

Who may not be able to join:

• You have already had your gallbladder removed, or have had certain procedures to examine or treat your bile ducts (called ERCP or endoscopic cholecystostomy)
• You have had one or more previous episodes of pancreatitis of any kind
• You are already on a waiting list at the same hospital to have your gallbladder removed, and that wait is less than 30 days
• You are being enrolled more than 3 days after being discharged from hospital for your pancreatitis
• You have taken a medication called ursodeoxycholic acid (UDCA) in the last 5 years, or it has been tried before and did not dissolve your gallstones
• You are allergic to, cannot tolerate, or have a medical reason not to take UDCA — for example, an active stomach or intestinal ulcer, certain liver or gut conditions, or you are breastfeeding (confirm with trial site)
• You have stones in your bile duct (not just the gallbladder), detected by a scan before joining the trial
• You drink heavily — 5 or more alcoholic drinks per day if you are a man, or 3 or more if you are a woman — or there is a strong suspicion of a significant alcohol problem
• You have a recent history of not following medical treatment as directed, or have personal circumstances that would make it hard to attend follow-up appointments
• Your blood triglyceride (fat) levels are above 400 mg/dL during your hospital stay, or you have a history of severely high triglycerides that are difficult to control
• You have chronic (long-term) pancreatitis, shown by calcium deposits in the pancreas or a widened pancreatic duct of 4mm or more
• You have cysts on your pancreas that are not related to your current pancreatitis episode
• You have a narrowing of the main pancreatic duct (confirm with trial site)
• You have a condition called primary hyperparathyroidism (a problem with one of the glands in your neck that affects calcium levels)
• You are pregnant

Important: Always verify eligibility with the trial site directly before applying.