Stroke Trial, Recruiting (NCT04948749)

Stroke Trial, Recruiting NCT04948749 Sponsor: Beijing Tiantan Hospital Condition: Stroke

Printed from Voxsanity (voxsanity.com.au) — NCT04948749 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Stroke

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

You are between 18 and 85 years old
You have had an ischemic stroke (a stroke caused by a blocked blood vessel) within the last 30 days, linked to a 70%–99% narrowing of a major artery inside the brain, as seen on a special scan called a CTA
The affected blood vessel measures between 2.0mm and 4.5mm in diameter (confirm with trial site)
The narrowed section of the artery is no longer than 14mm (confirm with trial site)
Your level of disability after the stroke is mild to moderate, based on a standard medical scoring scale called the modified Rankin Scale (confirm with trial site)
You understand what the study involves and have agreed in writing to take part

Who may not be able to join:

Your stroke happened fewer than 7 days before joining the study
You have additional significant narrowing or blockages in blood vessels near the affected artery (with some exceptions — confirm with trial site)
You have narrowing in both vertebral arteries (arteries at the back of the brain) and it is unclear which one caused your stroke (with some exceptions — confirm with trial site)
You have narrowing in only one vertebral artery while the other is completely normal
Your stroke was caused by a blockage in a very small, specific type of artery called a perforating artery
Your scan shows heavy calcium deposits at the site of the narrowing
You have had any bleeding in or around the brain in the past 6 weeks
Your artery narrowing is caused by a condition other than fatty buildup in the arteries (such as certain diseases, infections, or other medical conditions — confirm with trial site)
You have previously had a stent placed in an artery inside your brain
You have a known heart condition that is likely causing blood clots to travel to the brain
You have a brain tumour, a brain aneurysm, or an abnormal tangle of blood vessels in the brain
You are unable to take two blood-thinning medications at the same time
You have allergies or medical reasons that prevent you from receiving heparin, rapamycin, contrast dye, or anaesthesia
Your blood count results are below certain levels (low haemoglobin or low platelets — confirm with trial site)
You have serious liver or kidney problems
Your blood does not clot normally and this cannot be corrected (confirm with trial site)
You have had major surgery in the past 30 days or have major surgery planned within the next 90 days
You also need treatment at the same time for narrowing in the kidney, hip, or heart arteries
Your life expectancy is less than one year
You are pregnant or breastfeeding
You have a cognitive, emotional, or mental health condition that would prevent you from attending follow-up appointments
The trial doctors have another medical reason they feel makes participation unsuitable for you
You are already taking part in another clinical study that could interfere with this one

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 5 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Yongjun Wang, MD, Beijing Tiantan Hospital

Phone: 13581889908

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT04948749

Sponsor: Beijing Tiantan Hospital

Phase: Not Applicable

Status: Recruiting

Condition: Stroke

Trial contact: 13581889908

More information: https://clinicaltrials.gov/study/NCT04948749

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

You are between 18 and 85 years old
You have had an ischemic stroke (a stroke caused by a blocked blood vessel) within the last 30 days, linked to a 70%–99% narrowing of a major artery inside the brain, as seen on a special scan called a CTA
The affected blood vessel measures between 2.0mm and 4.5mm in diameter (confirm with trial site)
The narrowed section of the artery is no longer than 14mm (confirm with trial site)
Your level of disability after the stroke is mild to moderate, based on a standard medical scoring scale called the modified Rankin Scale (confirm with trial site)
You understand what the study involves and have agreed in writing to take part

Who may not be able to join:

Your stroke happened fewer than 7 days before joining the study
You have additional significant narrowing or blockages in blood vessels near the affected artery (with some exceptions — confirm with trial site)
You have narrowing in both vertebral arteries (arteries at the back of the brain) and it is unclear which one caused your stroke (with some exceptions — confirm with trial site)
You have narrowing in only one vertebral artery while the other is completely normal
Your stroke was caused by a blockage in a very small, specific type of artery called a perforating artery
Your scan shows heavy calcium deposits at the site of the narrowing
You have had any bleeding in or around the brain in the past 6 weeks
Your artery narrowing is caused by a condition other than fatty buildup in the arteries (such as certain diseases, infections, or other medical conditions — confirm with trial site)
You have previously had a stent placed in an artery inside your brain
You have a known heart condition that is likely causing blood clots to travel to the brain
You have a brain tumour, a brain aneurysm, or an abnormal tangle of blood vessels in the brain
You are unable to take two blood-thinning medications at the same time
You have allergies or medical reasons that prevent you from receiving heparin, rapamycin, contrast dye, or anaesthesia
Your blood count results are below certain levels (low haemoglobin or low platelets — confirm with trial site)
You have serious liver or kidney problems
Your blood does not clot normally and this cannot be corrected (confirm with trial site)
You have had major surgery in the past 30 days or have major surgery planned within the next 90 days
You also need treatment at the same time for narrowing in the kidney, hip, or heart arteries
Your life expectancy is less than one year
You are pregnant or breastfeeding
You have a cognitive, emotional, or mental health condition that would prevent you from attending follow-up appointments
The trial doctors have another medical reason they feel makes participation unsuitable for you
You are already taking part in another clinical study that could interfere with this one

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 5 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Beijing Tiantan Hospital

Registry

ClinicalTrials.gov

Start date

2 July 2021

Est. completion

1 December 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Any stroke or death within 30 days of enrollment or any revascularization procedure OR an ischemic stroke in the territory of the symptomatic intracranial artery between 31 day to 1 year.; Severe or moderate bleeding (GUSTO score)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 5 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov