Phase 1 Lymphoma Trial, Recruiting NCT04972942 Sponsor: New York Medical College Condition: Lymphoma
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Phase 1 Lymphoma Trial, Recruiting

NCT04972942
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 0 to 39 years old
  • People with T-cell acute lymphoblastic leukaemia (a type of blood cancer) who are in their second or later remission, meaning less than 5% cancer cells are detected in the bone marrow
  • People with relapsed T-cell lymphoblastic lymphoma (a related blood cancer) who have responded fully to re-induction treatment (treatment given to bring the cancer back under control), including cases where a secondary cancer is present (confirm with trial site)
  • People who have a planned stem cell transplant using a donor's cells, with a suitable donor already identified
  • People whose general health and physical functioning score is 60% or above on a standard medical performance scale
  • People who have fully recovered from the side effects of any previous chemotherapy, immunotherapy, or radiation treatment
  • People whose organ function (such as liver, kidneys, and heart) meets the trial's required levels
  • People or their guardians who have signed the trial's consent forms approved by an ethics review board

Who may not be able to join:

  • People who have previously had a stem cell transplant of any kind, whether using their own cells or a donor's cells
  • People who have an active, uncontrolled infection at the time of joining the trial
  • People with known allergies or serious reactions to mannitol, sorbitol, corticosteroids (a type of anti-inflammatory medication), monoclonal antibodies, human proteins, or related ingredients
  • People who are pregnant or currently breastfeeding
  • People who test positive for HIV, hepatitis B, or hepatitis C
  • People with chronic obstructive pulmonary disease (COPD), a long-term lung condition
  • People with asthma
  • People with significant heart disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Mitchell Cairo, MD, New York Medical College

Phone: 6172857844

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
New York Medical College
Registry
ClinicalTrials.gov
Start date
22 May 2023
Est. completion
1 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Patients with dose limiting toxicity (per CTCAE v.5)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov