Phase 2 Breast Cancer Trial, Recruiting NCT04993014 Sponsor: AC Camargo Cancer Center Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT04993014
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with HER2-positive breast cancer (with or without hormone receptors)
  • Your cancer is at an early to locally advanced stage (Stage I, II, or III)
  • Your doctors plan to treat you with chemotherapy plus the targeted drugs trastuzumab and pertuzumab before surgery (any chemotherapy regimen is accepted)
  • You are planning to have breast surgery after completing the pre-surgery treatment
  • Your thinking, memory, and understanding are not significantly affected
  • Your general health and ability to carry out daily activities meets a certain level of functioning (confirm with trial site)
  • For the later part of the trial: your cancer has completely disappeared from breast tissue and lymph nodes after the pre-surgery treatment, as confirmed by a tissue sample
  • You are willing to take part and have signed the informed consent form

Who may not be able to join:

  • You have a medical reason why you cannot receive trastuzumab or pertuzumab
  • You need additional chemotherapy after surgery (hormone therapy after surgery is allowed)
  • You have been diagnosed with another cancer within the last 5 years — although certain exceptions may apply, such as a treated non-melanoma skin cancer or cervical cancer that has not spread (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 16 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Marcelle G Cesca, MD, A.C. Camargo Cancer Center

Phone: +551121895000

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
AC Camargo Cancer Center
Registry
ClinicalTrials.gov
Start date
1 March 2021
Est. completion
30 April 2024

Where this trial is recruiting

🇧🇷 Brazil

Primary endpoints

HER2 therapy disease-free survival; CTCs disease-free survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 16 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov