Phase 3 Myeloma Trial, Recruiting NCT05020236 Sponsor: Pfizer Condition: Myeloma
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Phase 3 Myeloma Trial, Recruiting

NCT05020236
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have previously been diagnosed with multiple myeloma, according to standard diagnostic guidelines
  • People whose multiple myeloma can be measured through blood or urine tests showing certain levels of abnormal proteins (confirm with trial site for specific values)
  • People who have already received treatment for multiple myeloma, including a drug called lenalidomide
  • People who are reasonably active and able to carry out daily activities, with only mild limitations at most (based on a standard medical scoring system)
  • People whose side effects from any previous treatment have mostly cleared up or are very mild
  • People who are not pregnant and are willing to use contraception during the trial

Who may not be able to join:

  • People who have the early, inactive form of multiple myeloma known as "smoldering" myeloma
  • People who have plasma cell leukemia (a related but different blood condition)
  • People who have amyloidosis (a condition where abnormal proteins build up in organs)
  • People who have POEMS syndrome (a rare disorder related to abnormal blood cells)
  • People who have had a stem cell transplant within the 12 weeks before joining, or who are experiencing complications from a previous transplant affecting the immune system
  • People with active hepatitis B, hepatitis C, COVID-19, HIV, or any other active, uncontrolled infection (bacterial, fungal, or viral)
  • People who have had another cancer within the past 3 years, except for certain treated skin cancers or very early-stage cancers that have been fully treated
  • People who have previously received a treatment that targets a protein called BCMA on myeloma cells
  • People who have received a live vaccine within 4 weeks before starting the trial
  • People who have taken part in another clinical trial or received an experimental treatment within 30 days before starting this trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Pfizer CT.gov Call Center, Pfizer

Phone: 1-800-718-1021

Australian sites

Pindara Private Hospital, Benowa, Queensland
QScan Radiology Clinics, Clayfield, Queensland
Gallipoli Medical Research Foundation, Greenslopes, Queensland
Slade Pharmacy, Richmond, Victoria
Linear Clinical Research, Perth, Western Australia

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Registry
ClinicalTrials.gov
Start date
4 October 2021
Est. completion
27 April 2026

Where this trial is recruiting

🇦🇷 Argentina 🇦🇺 Australia 🇧🇷 Brazil 🇨🇦 Canada 🇨🇳 China 🇨🇿 Czechia 🇫🇮 Finland 🇫🇷 France 🇩🇪 Germany 🇬🇷 Greece 🇮🇹 Italy 🇯🇵 Japan 🇲🇽 Mexico 🇳🇿 New Zealand 🇳🇴 Norway 🇵🇱 Poland 🇪🇸 Spain 🇸🇪 Sweden 🇹🇼 Taiwan Turkey (Türkiye) 🇬🇧 United Kingdom 🇺🇸 United States

5 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Part 1 Safety Lead-In: Incidence of dose limiting toxicities; Part 2 Randomized: Progression free survival per International Myeloma Working Group criteria; Part 3: Frequency of treatment-emergent adverse events

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov