Myeloma

**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing the consent form - You have been diagnosed with Multiple Myeloma (a type of blood cancer) confirmed by a lab test - You have already received at least 3 different treatment regimens for your myeloma, including one from...

Who might be able to join this trial: - You have previously been diagnosed with multiple myeloma - Your doctor has determined that you are suitable for a stem cell transplant using your own stem cells (called an autologous stem cell transplant) - Your recent blood or lab test results meet certain levels required by the...

**Who might be able to join this trial:** - You must be 18 years old or older. - You must be well enough to carry out basic daily activities, with only mild limitations at most (confirm with trial site for exact fitness level required). - Your doctor expects you to live for at least 3 more months. - You have already be...

**Who might be able to join this trial:** - You have been diagnosed with smoldering multiple myeloma (a early, inactive form of blood cancer) for less than 5 years. - Your smoldering multiple myeloma has been confirmed as intermediate or high risk, and you are generally able to carry out normal daily activities with li...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma and the disease can be measured through specific blood, urine, or protein tests. - You have previously been treated with two specific types of myeloma drugs — an immunomodulatory drug (IMiD) and a proteasome inhibitor (PI) — each...

**Who might be able to join this trial:** - People aged 18 or older. - People whose general health and ability to carry out daily activities meets a certain level of functioning (rated 0 or 1 on a standard oncology scale — confirm with trial site). - People with multiple myeloma (MM) that has come back or stopped resp...

**Who might be able to join this trial:** - You are generally able to carry out basic daily activities, even if you need some help at times (this is measured on a standard scale called ECOG, scores 0–2). - You have been officially diagnosed with multiple myeloma, confirmed by a protein marker found in your blood and/o...

**Who might be able to join this trial:** - People who have previously been diagnosed with multiple myeloma, according to standard diagnostic guidelines - People whose multiple myeloma can be measured through blood or urine tests showing certain levels of abnormal proteins (confirm with trial site for specific values)...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma (according to standard international diagnostic guidelines) and have already completed an initial course of treatment, which may or may not have included a consolidation phase. - People who have received only one cour...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (a type of blood cancer) and your disease can be measured through specific blood, urine, or lab tests. - You have received between 1 and 3 previous treatments for multiple myeloma. - At least one of your previous myeloma treatmen...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma according to standard international diagnostic guidelines - People who have been newly diagnosed and are not suitable for high-dose chemotherapy with a stem cell transplant — either because of older age, because other heal...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (MM) according to recognised international diagnostic standards - People whose general health and ability to carry out daily activities falls within an acceptable range on a standard medical scale (scores 0, 1, or 2 out of...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (a type of blood cancer) according to established medical guidelines. - People whose multiple myeloma is measurable through specific blood, urine, or protein tests meeting set thresholds (confirm with trial site for exact...

Who might be able to join this trial: - People who have given written consent to participate in the study - People who are older than 18 years of age at the time of signing the consent form - People who have been formally diagnosed with multiple myeloma according to established international diagnostic guidelines - Peo...

Who might be able to join this trial: - People aged 18 years or older - People who have been diagnosed with chronic lymphocytic leukaemia (CLL), multiple myeloma (MM), or non-Hodgkin lymphoma (NHL) - People who have been receiving immunoglobulin (Ig) therapy — given either through a drip or an injection under the skin...

**Who might be able to join this trial:** - People who are at least 18 years old (or the legal age of consent in the country where the trial is taking place) at the time of signing the consent form. - People who have a confirmed diagnosis of Multiple Myeloma (MM) based on tissue or cell testing, and whose disease has...

**Who might be able to join this trial:** - Adults aged 18 or older (or the legal age of an adult in their country) at the time of the first screening visit - People whose general health and ability to carry out daily activities meets a certain minimum level — those with a score of 0 or 1 on a standard medical scale,...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (a type of blood cancer) confirmed by laboratory testing, and whose disease can be measured through blood, urine, or imaging tests - People who are reasonably active and able to care for themselves, with only limited diffic...

**Who might be able to join this trial:** - You are generally able to carry out daily activities and care for yourself, with little or no limitation from your illness (this is measured by a standard scoring system called ECOG, scores 0 or 1) - You have been diagnosed with multiple myeloma that has come back after treat...

**Who might be able to join this trial:** - You are 18 years of age or older (for the first part of the study, you must be between 18 and 75 years old) - You have been officially diagnosed with multiple myeloma according to established diagnostic guidelines - You are generally able to carry out everyday activities with...

**Who might be able to join this trial:** - People who are at least 18 years old (or the legal age of consent in the country where the trial is taking place) - People whose overall health and ability to carry out daily activities meets a specific level, as measured by a standard oncology scoring system (the required l...

**Who might be able to join this trial:** - People who have previously been diagnosed with multiple myeloma and have already received between 1 and 4 rounds of treatment, including a type of drug that targets a protein called CD38 and a drug called lenalidomide. - People whose myeloma has started growing again or did...

**Who might be able to join this trial:** - People who are reasonably active and able to carry out daily activities (as measured by a standard health performance scale, scored 0–2) - People who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment - People whose myeloma can be...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma according to internationally recognised diagnostic standards, and whose disease can be measured through specific blood or urine tests at the time of screening. - People whose multiple myeloma has come back after previously...

**Who might be able to join this trial:** - People who have previously been diagnosed with multiple myeloma, confirmed using standard international diagnostic criteria. - People whose multiple myeloma is still detectable through specific blood or urine tests measuring abnormal proteins produced by the cancer. - (Part...

**Who might be able to join this trial:** - People diagnosed with one of the following conditions: MGUS (an abnormal protein condition that may lead to blood cancer), smouldering multiple myeloma (an early, inactive form of multiple myeloma), multiple myeloma (with or without tumours outside the bone marrow), or plasm...

**Who might be able to join this trial:** - You have been officially diagnosed with a blood cancer called multiple myeloma (MM) - You have already received at least 4 different types of myeloma treatments, including specific drug types known as IMiDs, proteasome inhibitors, anti-CD38 therapy, and anti-BCMA therapy, acr...

**Who might be able to join this trial:** - People who have multiple myeloma that has come back after treatment or has stopped responding to treatment. - People who have received at least 1 but no more than 3 previous treatment courses for multiple myeloma, which may have included certain types of drugs such as a prot...

Who might be able to join this trial: - People who have been formally diagnosed with multiple myeloma and still have signs of the disease that can be measured. - People who use contraception in line with the rules that apply in their country for those taking part in clinical studies. **For the first part of the trial...

**Who might be able to join this trial:** - People whose physical functioning and activity level meets a specific standard, rated 0 or 1 on a medical scale used to measure how well a person can carry out daily activities (confirm with trial site) - People with multiple myeloma who have already received at least 3 diff...

**Who might be able to join this trial:** - You are 18 years of age or older (or the legal age of consent in your country) at the time of signing the consent form. - You are able to understand and sign a consent form and agree to follow the study rules. - You have been newly diagnosed with multiple myeloma and your do...

**Who might be able to join this trial:** - You have been officially diagnosed with multiple myeloma based on standard diagnostic guidelines - Depending on which treatment group applies to you: you have had 1 to 3 previous treatments for multiple myeloma (including specific drug types called proteasome inhibitors and...

Who might be able to join this trial: - You are generally able to carry out daily activities and care for yourself, with little or no limitation due to your illness (this is measured by a standard scale called ECOG, with a score of 0 or 1) - You have been diagnosed with multiple myeloma that has come back or stopped re...

Who might be able to join this trial: - People who have been diagnosed with symptomatic multiple myeloma, confirmed using standard international guidelines. - People who have been assessed as not suitable for high-dose chemotherapy followed by a stem cell transplant using their own cells. - People whose myeloma can be...

**Who might be able to join this trial:** - People who have been formally diagnosed with multiple myeloma using standard international diagnostic guidelines. - People whose disease is measurable through at least one of the following blood or urine tests (taken within 28 days before enrolling): a specific abnormal prot...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of Multiple Myeloma (MM) based on internationally recognised guidelines. - People who have recently started a treatment called teclistamab within the first 8 weeks of their planned treatment schedule, and who are expected to continue it...

Who might be able to join this trial: - People who have multiple myeloma that has come back after treatment and is no longer responding to treatment, with signs of the disease that can be measured and tracked. - People who have already been through at least 3 previous rounds of treatment for their myeloma, including sp...

Who might be able to join this trial: - Adults aged 18 years or older - People who have been diagnosed with a blood cancer, specifically chronic lymphocytic leukaemia (CLL), multiple myeloma (MM), or non-Hodgkin's lymphoma (NHL) - People whose treating doctor has determined them eligible for immunoglobulin (Ig) replace...

Who might be able to join this trial: - People who have been receiving a standard dose of intravenous immunoglobulin (IVIg) treatment regularly for at least 6 months in a row, to help prevent bacterial infections caused by low antibody levels in the blood. - People whose treating doctor has decided that stopping IVIg t...

Who might be able to join this trial: - The inclusion criteria section does not list any specific requirements for joining this part of the trial (confirm with trial site) Who may not be able to join: - People who have previously had, or are planned to have, a stem cell transplant using cells from another person - Peo...

Who might be able to join this trial: - People who have been receiving immunoglobulin (Ig) replacement therapy — either through a drip (IV) or under the skin (subcutaneous) — for at least 6 months in a row, to help prevent bacterial infections due to low antibody levels. - People whose treating doctor believes it is ap...

**Who might be able to join this trial:** - People who have relapsed or refractory multiple myeloma (meaning the cancer has come back or stopped responding to treatment) and have received at least 1 but no more than 3 previous lines of treatment, which must have included a drug called lenalidomide and at least one othe...

**Who might be able to join this trial:** - People who have been formally diagnosed with multiple myeloma (a type of blood cancer) according to recognised international diagnostic standards, with signs of the disease that can be measured by a central laboratory at the time of screening - People who have already receiv...

**Who might be able to join this trial:** - You are 18 years old or older - You have been formally diagnosed with multiple myeloma based on recognised diagnostic standards - Your myeloma can be measured through specific blood or urine tests showing certain protein levels above set thresholds (confirm with trial site)...

Who might be able to join this trial: - People who have relapsed or treatment-resistant multiple myeloma and have already tried at least 3 lines of treatment, with no remaining standard treatment options expected to provide meaningful benefit (or who are not suitable candidates for those options) - People who have a go...

**Who might be able to join this trial:** - You are 18 years of age or older at the time of signing the consent form - Your body weight relative to your height (BMI) falls between 18.5 and just under 28 - You are willing to take part, understand what the study involves, and agree to sign a consent form - You have been...

**Who might be able to join this trial:** - People who have been formally diagnosed with multiple myeloma (a type of blood cancer) according to international diagnostic standards, with signs of the disease that can be measured by a central laboratory at the time of screening - People who have already received between...

**Who might be able to join this trial:** - People who have signed the study's official consent form - People aged 18 or older at the time of signing the consent form - People whose general physical functioning is rated at a level that allows them to care for themselves and be up and about for at least half of waking...

Who might be able to join this trial: - People who are generally well enough to carry out daily activities with little to no limitation, as measured by a standard cancer health scale (a score of 0 or 1 on the ECOG scale). - People who are expected to live for at least 12 weeks. - People who have been diagnosed with mul...

**Who might be able to join this trial:** - You must be 18 years old or older at the time of signing the consent form. - You must have been diagnosed with Multiple Myeloma (MM) confirmed by a lab test (tissue or cell sample). - You must have already received at least 3 different previous treatments for myeloma, includ...

**Who might be able to join this trial:** - You received a stem cell transplant from a donor (called an allogeneic transplant) as part of an NHLBI research study at the NIH, and it was either an experimental or standard treatment - Or, in some special cases, you may be eligible if your donor stem cell transplant was d...

**Who might be able to join this trial:** - People who have a personal history of lymphoma, a blood cancer called multiple myeloma, or related blood and immune system cancers, or who have family members with these conditions. - People whose family includes members across multiple generations who have been diagnosed wi...

**Who might be able to join this trial:** - People who have at least 2 living blood relatives (such as siblings, parents, or cousins) who have been diagnosed with a lymphoproliferative disorder (a type of condition affecting the lymph system, such as certain cancers or immune system diseases) **Who may not be able to...

Who might be able to join this trial: - You have been diagnosed with amyloidosis, or your doctor suspects you may have it - You have been referred to the Amyloid Treatment and Research Center at Boston University Medical Center Who may not be able to join: - There are no specific reasons listed that would prevent some...

**Who might be able to join this trial:** **For adults (age 18 and older):** - You are being evaluated or treated for cancer at the NIH Clinical Center or a participating site - You have been newly diagnosed with cancer and have not yet started treatment, OR your cancer has come back or is getting worse despite treatm...

Who might be able to join this trial: - People who have been diagnosed with a solid tumour or blood cancer confirmed through a tissue sample (biopsy) - People who are waiting for a biopsy or surgery to investigate a lump or mass that was found during an examination or routine scan - People who are able to lie still ins...

Who might be able to join this trial: - People who have been diagnosed with a blood or immune system cancer or disorder, including: Acute myeloid leukemia, Acute lymphoblastic leukemia, Chronic myelogenous leukemia, Chronic lymphoid leukemia, Non-Hodgkin lymphoma, Hodgkin lymphoma, Myelodysplastic syndromes, Myeloproli...

"Who might be able to join this trial: - People who have an appointment at the North Carolina Cancer Hospital and agree to complete a Geriatric Assessment (a series of questions and tasks used to understand the overall health and wellbeing of older adults) - People who are able to read and speak English Who may not be...

Who might be able to join this trial: - You have a condition affecting the blood system (such as a disease you were born with, one that developed over time, or one caused by strong treatments that destroyed your bone marrow) - You (or your guardian) have signed a consent form agreeing to take part before the study begi...

"Who might be able to join this trial: - People who have been diagnosed with a plasma cell dyscrasia (a type of blood disorder where abnormal protein is produced by certain blood cells) Who may not be able to join: - People who are currently incarcerated, as standard access to the Ohio State myeloma clinic would not b...

Who might be able to join this trial: **If you have a known blood cancer (lymphoid malignancy):** - You have been diagnosed with a lymphoid blood cancer or a condition that may lead to one, such as multiple myeloma, Hodgkin's lymphoma, diffuse large B-cell lymphoma, or similar conditions - Your diagnosis has been or c...

**Who might be able to join this trial:** - People who are 18 years of age or older - People who are being seen as an outpatient or are staying in hospital with a suspected blood cancer that needs further investigation, OR people who have already been diagnosed with a blood cancer within the last 6 months at the time o...

**Who might be able to join this trial:** - People who have a known or suspected early-stage or precursor blood cancer condition, including: - Early-stage myelodysplastic syndrome (MDS) at a low or very low risk level, or unexplained low blood cell counts that haven't been fully diagnosed - Conditions that may lea...

**Who might be able to join this trial:** - People aged 18 or older who have given written consent to participate. - People with a confirmed diagnosis of multiple myeloma that has come back or stopped responding to treatment, with measurable signs of the disease in blood or urine tests. - People whose myeloma is causi...

**Who might be able to join this trial:** - You have been diagnosed with a plasma cell disorder (a type of blood/bone marrow condition, such as multiple myeloma) - Your treatment plan includes a stem cell transplant using your own stem cells (called an autologous transplant) - You are between 18 and 80 years old - You...

**Who might be able to join this trial:** - You have been diagnosed with cancer, a pre-cancerous condition, or a disease (such as an immune system disorder) that raises your risk of developing cancer or a pre-cancerous condition - You are 18 years of age or older - You are reasonably functional in daily life — not full...

**Who might be able to join this trial:** - You have been diagnosed with a condition called MGUS (monoclonal gammopathy of undetermined significance), meaning your blood or urine shows a small abnormal protein, less than 10% of your bone marrow cells are abnormal plasma cells, and you have no signs of active disease o...

**Who might be able to join this trial:** - People diagnosed with acute myelogenous leukemia (AML) where initial treatment did not work, where the disease has come back, or where the disease has features that make relapse more likely (such as certain genetic changes or signs of remaining cancer cells) - People diagnos...

"Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (a type of blood cancer affecting plasma cells in the bone marrow) Who may not be able to join: - People whose multiple myeloma diagnosis was made before 1st January 2008 Important: Always verify eligibility with the trial s...

**Who might be able to join this trial:** - You have a disease or condition that can be treated with a stem cell transplant, such as certain immune system disorders (for example, Severe Combined Immunodeficiency or Wiskott-Aldrich Syndrome), bone marrow failure conditions, metabolic diseases (such as Hurler's Syndrome...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (a type of blood cancer affecting plasma cells in the bone marrow), confirmed through specific bone marrow, blood, or urine test results that meet established diagnostic standards. - People whose multiple myeloma is curren...

**Who might be able to join this trial:** - You must be enrolled in Medicare - You have been diagnosed with stage II or III multiple myeloma (a type of blood cancer) and/or a condition called primary plasma cell leukemia - Your doctors have decided you are suitable to receive a stem cell transplant using cells donated...

**Who might be able to join this trial:** - People diagnosed with multiple myeloma whose cancer cells test positive for a marker called CD138 or BCMA - People who have no remaining curative treatment options available, such as stem cell transplants - People whose multiple myeloma has come back or stopped responding to...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (a type of blood cancer) confirmed by a specific protein marker, and there are no longer any treatment options available to cure it (including stem cell transplants). - You have not been able to reach complete remission (where no...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with an incurable, spreading (metastatic) solid tumour (not including primary brain tumours), multiple myeloma, or certain types of B cell non-Hodgkin lymphoma, where no standard life-extending treatment is available or the per...

Who might be able to join this trial: - People who have multiple myeloma and need systemic (whole-body) treatment, currently in their third line of treatment (note: first-line and second-line recruitment is closed) - People who are 18 years of age or older - People who are willing and able to sign a written consent for...

Who might be able to join this trial: - People aged 60 or younger (some disease-specific exceptions may apply — confirm with trial site) - People with a reasonable level of physical functioning, as measured by standard performance scales used by doctors - People (or their parent, guardian, or legal representative) who...

"Who might be able to join this trial: - You must have already enrolled in a CAR-T cell therapy study at Froedtert Hospital & the Medical College of Wisconsin. Who may not be able to join: - There are no rules that would stop someone from joining this trial, as long as they meet the requirement above. Important: Alwa...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma that has come back (relapsed), with signs of the disease that can be measured, and who have previously been treated with a stem cell transplant using their own cells (ASCT). - People whose myeloma first came back at least...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing consent forms - People who have been diagnosed with, or are suspected to have, one of the following conditions: a protein abnormality in the blood called MGUS (Monoclonal Gammopathy of Undetermined Significance), smol...

Who might be able to join this trial: - You are 30 years old or older - You identify yourself as African American, OR you have a parent, child, or sibling who has been diagnosed with a blood-related condition such as MGUS, SMM, multiple myeloma, Waldenström's Macroglobulinemia, or another blood cancer - If you are betw...

**Who might be able to join this trial:** - People who are relatively active and able to carry out daily activities, with a fitness score of 0 or 1 on a standard oncology scale (called ECOG performance status). - People who have a confirmed diagnosis of active Multiple Myeloma (MM), diagnosed using standard internatio...

Who might be able to join this trial: - People who are seeing a doctor because they have been newly diagnosed with, or have had a return of, Multiple Myeloma (a type of blood cancer), based on internationally recognised diagnostic standards - People who have agreed to take part in the study and to have biological sampl...

**Who might be able to join this trial:** - People who have a bone lesion (abnormal area) in the shaft or neck of the femur (thigh bone) - People who are 18 years of age or older - People who are already planned to have a preventive surgical nail inserted into one thigh bone (a procedure to strengthen the bone before i...

**Who might be able to join this trial:** - People diagnosed with multiple myeloma (a type of blood cancer) who are starting their first treatment and are not suitable candidates for a stem cell/bone marrow transplant using their own cells - People whose treatment plan matches one of the standard treatments recommende...

**Who might be able to join this trial:** **About the patient's diagnosis:** - People diagnosed with one of the following blood cancers (confirmed by tissue testing): Acute Myeloid Leukaemia (AML) that is in remission or not rapidly worsening; Myelodysplastic Syndrome (MDS); Chronic Myeloid Leukaemia (CML) in a stable...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (a type of blood cancer affecting bone marrow), confirmed by a tissue sample test. - You have a painful bone lesion (a specific affected area called the "index lesion") that can be seen on a scan or X-ray. - You may have had any n...

**Who might be able to join this trial:** - People who have given written consent to participate voluntarily, before any study-related procedures begin. - People who have a confirmed diagnosis of multiple myeloma with measurable disease shown through specific blood, urine, or bone marrow tests (confirm with trial site...

**Who might be able to join this trial:** - You have been diagnosed with high-risk "smoldering multiple myeloma" (an early, symptom-free stage of myeloma) within the last 12 months, and your condition is considered high-risk based on at least 2 specific laboratory or genetic markers (confirm with trial site). - A bone...

**Who might be able to join this trial:** - You are willing and able to give written consent to participate - You are between 18 and 75 years old (possibly older if considered healthy enough by the doctors) - You have been diagnosed with AML, ALL, DLBCL, Burkitt lymphoma, multiple myeloma, or high-risk MDS (a type of...

Who might be able to join this trial: - You must be willing to participate and have signed a consent form agreeing to take part in the research - Your diagnosis must be based on the World Health Organization (WHO) 2008 guidelines (confirm with trial site) - You must have already tried all standard treatment options ava...

Who might be able to join this trial: - People who are able to give their informed consent to take part in the trial - People who have a confirmed diagnosis of multiple myeloma - People who are able to swallow and keep down oral (by mouth) medication - People from all ethnic backgrounds are welcome to apply Who may no...

Who might be able to join this trial: - People who have been diagnosed with a blood cancer, specifically either myeloma or acute leukaemia - People who are 18 years of age or older - People who are willing and able to give their informed consent to take part Who may not be able to join: - People who are currently preg...

**Who might be able to join this trial:** - People who are willing to give written consent to participate, with the understanding that they may withdraw from the trial at any time without affecting their future medical care. - People aged 18 or older, of any gender. - People who, according to their treating institutio...

**Who might be able to join this trial:** - People aged 18 or older who have been diagnosed with symptomatic myeloma (an active form of blood cancer) - People whose condition is considered stable by the doctor responsible for their care - People (or their carer) who are willing and considered able to learn how to give...

**Who might be able to join this trial:** - You are willing and able to sign a consent form agreeing to take part in the study - You have been diagnosed with multiple myeloma or a related plasma cell disease that has come back or stopped responding to treatment, AND at least one of the following applies: your cancer d...

**Who might be able to join this trial:** - People who are 60 years of age or older (all groups) - People who have a confirmed diagnosis of a relapsed or treatment-resistant blood cancer or plasma cell disorder (such as lymphoma or myeloma) and are receiving a commercially approved CAR T-cell therapy (all groups) - Peo...

Who might be able to join this trial: - You have been diagnosed with Multiple Myeloma for the first time, and this diagnosis was confirmed by a lab test (such as a biopsy) within the last 5 years - You were at least 21 years old when you were diagnosed - You were diagnosed in one of the 48 counties in California - You...

**Who might be able to join this trial:** - People who have just received a new diagnosis of multiple myeloma (not a previous or returning diagnosis) - People for whom doctors have determined that a stem cell transplant (using the patient's own stem cells) is an appropriate treatment option - People with a general hea...

**Who might be able to join this trial:** - People aged 18 or older at the time of signing the consent form. - People who have given written consent following guidelines set by federal, local, and institutional standards. - People with multiple myeloma (MM) that can be measured through blood or urine tests, based on s...

**Who might be able to join this trial:** - You have been diagnosed with a plasma cell cancer (such as multiple myeloma or a related condition) and your doctor has decided you need treatment. - If joining Phase A of the trial, you must have already received at least 2 previous lines of treatment for your condition, as...

**Who might be able to join this trial:** - People who have given written consent to take part (or whose legal representative has done so on their behalf) - People who agree to allow stored tumour tissue samples from a previous biopsy to be used (exceptions may be possible with approval from the lead researcher — conf...

**Who might be able to join this trial:** **Part One (initial entry):** - You have been newly diagnosed with multiple myeloma and are considered suitable for high-dose chemotherapy and a stem cell transplant - You are between 18 and 74 years old at the time of signing the consent form - Your multiple myeloma is detect...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (a type of blood cancer) - People who have one or more confirmed damaged areas in the spine between the mid-back and lower back (between the 6th thoracic and 5th lumbar vertebrae) - People who have 4 or fewer spinal fractures -...

**Who might be able to join this trial:** - People who have been diagnosed with active multiple myeloma, as defined by international medical guidelines. - People whose myeloma can be measured through a blood test showing a specific abnormal protein at a certain level, OR through a urine test showing abnormal protein l...

Who might be able to join this trial: - People who have been newly diagnosed with multiple myeloma according to standard medical criteria. - People who are generally well enough to carry out some daily activities (a health performance score of 0–2, or 3 only if the reduced score is due to pain). - People whose multiple...

**Who might be able to join this trial:** - You have been diagnosed (confirmed by lab testing of tissue) with a type of blood cancer that is either a certain type of leukemia (ALL) or lymphoma (NHL) with a specific protein marker called CD19, or a type of blood cancer called multiple myeloma (MM) with a marker called...

**Who might be able to join this trial:** *For people with Acute Myeloid Leukemia (AML):* - A diagnosis of AML that has been confirmed through laboratory tissue testing, and the cancer cells carry a specific protein called CD70 - The AML has come back or stopped responding to treatment, meaning either: standard chemot...

**Who might be able to join this trial:** - Adults aged 18 or older (or teenagers aged 13–17 who weigh at least 40 kg, for certain types of acute lymphoblastic leukemia) - People who have been diagnosed with certain advanced blood cancers that have come back or stopped responding to treatment, including: chronic lymph...

**Who might be able to join this trial:** - People who have signed a written consent form agreeing to take part - People who have been diagnosed with relapsed or refractory multiple myeloma or a related plasma cell disease, and whose cancer either did not respond to standard chemotherapy, came back after going into re...

**Who might be able to join this trial:** - People who have been diagnosed with intermediate- or high-risk smoldering multiple myeloma (a pre-cancer blood condition that has not yet caused organ damage) within the last 5 years, confirmed by specific lab or bone marrow test results. - People of any race, ethnic backgro...

**Who might be able to join this trial:** - People aged 18 or older - People who have multiple myeloma that has come back or stopped responding to treatment - People whose myeloma produces measurable proteins in the blood at levels that meet specific thresholds (confirm with trial site) - People who have already recei...

**Who might be able to join this trial:** - People aged 18 or older, of any gender. - People with a life expectancy of more than 12 weeks. - People whose general health and ability to carry out daily activities falls within a certain range, as measured by a standard cancer performance scale (scores 0 to 2 on the ECOG...

Who might be able to join this trial: - People who live in the West-Occitanie region (in France) - People who have been diagnosed with symptomatic multiple myeloma (a type of blood cancer that is causing symptoms, as defined by specific medical guidelines) Who may not be able to join: - People who do not wish to take...

**Who might be able to join this trial:** This trial has three groups (Arms), each with different criteria. Patients, their care-partners, and transplant team members may each be eligible separately. --- **Arm 1 — Patients:** Who might be able to join this trial: - People aged 60 or older who have been diagnosed wi...

**Who might be able to join this trial:** - You are 18 years old or older - You are a man or a woman - You are covered by a social security or health insurance system - You are having a specific type of stem cell transplant (using stem cells from the blood, not from umbilical cord blood) from a donor, for a blood cance...

Who might be able to join this trial: - Adults aged 18 or older who have been newly diagnosed with multiple myeloma and whose doctor has decided they need to start treatment, and who are reasonably physically active (able to carry out light daily activities at minimum). - People who have received little or no prior tre...

Who might be able to join this trial: - Both men and women can participate - You must be 18 years old or older - You have been diagnosed with active or symptomatic multiple myeloma (a type of blood cancer causing symptoms or certain measurable changes in the body) no earlier than 1st January 2019 - You are willing and...

**Who might be able to join this trial:** - People aged 18 or older who are able to understand the study and are willing to sign a consent form - People with a general health and activity level rated 0, 1, or 2 on a standard scale used by doctors to measure how much cancer affects daily functioning (confirm with trial...

**Who might be able to join this trial:** - People diagnosed with certain blood cancers or blood disorders, including acute myeloid leukemia, acute lymphoid leukemia (in remission), myelodysplasia (MDS), chronic lymphocytic leukemia (CLL) with little or no lymph node involvement, multiple myeloma, chronic myeloid leuk...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with multiple myeloma that has come back or stopped responding to previous treatment, in a way that matches the FDA's official guidelines for the drug isatuximab-irfc (Sarclisa®) - People whose treating doctor has conf...

**Who might be able to join this trial:** - People who have been diagnosed with high-risk smoldering multiple myeloma (a pre-cancer blood condition that has not yet become active), confirmed by all three of the following: at least 10% abnormal plasma cells found in a bone marrow sample, a reduction in certain normal a...

**Who might be able to join this trial:** - Your blood cancer cells must show a certain protein called CD70 on at least 10% of the cancer cells, confirmed by a lab test before enrollment. - You must meet additional eligibility requirements specific to your type of blood cancer (confirm with trial site). - It must have...

**Who might be able to join this trial:** - People who have been diagnosed with a slow-growing B-cell or T-cell blood cancer called Non-Hodgkin lymphoma (including lymphomas affecting the skin), or a type of Non-Hodgkin lymphoma with a variable course such as mantle cell lymphoma, with measurable signs of disease - Pe...

Who might be able to join this trial: **Stem Cell Transplant Group:** - People who are willing to give their informed consent to take part in the study - People who are willing to follow all study procedures and stay involved for the full duration of the study - People who have a confirmed diagnosis of multiple myelom...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with a condition called monoclonal gammopathy of undetermined significance (MGUS), where certain protein levels in the blood or urine are below specific thresholds, less than 10% of bone marrow cells are abnormal plasma cells,...

**Who might be able to join this trial:** - People who are relatively well and able to carry out daily activities with little to no limitation (as measured by a standard health scale used in cancer research) - People whose multiple myeloma can be measured and tracked using standard methods agreed upon by international...

**Who might be able to join this trial:** - People who have given written consent to participate and agree to allow their personal health information to be used for the study, understanding they may withdraw at any time. - People who are willing and able to follow the study visit schedule and other study requirements,...

**Who might be able to join this trial:** - You have been officially diagnosed with multiple myeloma (a type of blood cancer) according to recognised international standards. - You are generally able to carry out daily activities with little to no limitation (your doctor rates your physical ability as 0, 1, or in some...

Who might be able to join this trial: **Patients:** - People who have been diagnosed with a blood cancer and have a stem cell transplant or CAR T-cell therapy scheduled. - People who can speak, read, and understand English, or who are able to fill out questionnaires with some help from an interpreter. **Family caregi...

**Who might be able to join this trial:** - People who are reasonably physically functional in daily life, as assessed by a standard medical scale (called ECOG), with a score of 2 or lower, measured within 30 days before joining the trial - People who have been diagnosed with multiple myeloma, as defined by internatio...

Who might be able to join this trial: - You must have already received at least one dose of a treatment called cilta-cel as part of a previous company-sponsored clinical trial - You must be willing and able to give your consent to take part in this study Who may not be able to join: - No specific exclusion criteria we...

Who might be able to join this trial: - People aged 18 or older who are already enrolled in a specific related clinical trial called the CONFIRM phase III trial (ClinicalTrials.gov identifier: NCT03836014) - People who are still receiving treatment at around the 2-year mark (within 3 months either side) after being ran...

**Who might be able to join this trial:** - People who have multiple myeloma and have had a stem cell transplant using their own stem cells (called an autologous transplant) within one year of being diagnosed, and whose disease responded at least partially to treatment after the transplant — enrolment must happen betw...

**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender - People who have already been through at least 3 previous treatment plans for their cancer, including treatments from two specific drug groups: proteasome inhibitors and immunomodulatory agents - People whose multiple myeloma or...

**Who might be able to join this trial:** - Adults aged 18 or older (there is no upper age limit) who have been newly diagnosed with multiple myeloma and whose doctors have determined that treatment should begin. - People whose multiple myeloma is measurable through specific blood, urine, or protein tests at the time...

**Who might be able to join this trial:** - Your bone marrow biopsy (taken within the last 30 days) must show that at least 10% of your bone marrow cells are myeloma (plasma) cells. - You must have a confirmed diagnosis of multiple myeloma. - Your myeloma must be measurable through at least one of the following: a spe...

Who might be able to join this trial: - People who are enrolled in or covered by a social security scheme - People who have signed a written consent form agreeing to take part - People who have been diagnosed with multiple myeloma for the first time (meaning it has not been treated before) and whose condition requires...

**Who might be able to join this trial:** - People who are able to understand and agree to the study's consent process by signing a consent form - People who are aged 65 years or older at the time of signing the consent form - People who are able to follow the study visit schedule and meet all study requirements - Peo...

Who might be able to join this trial: - People who are reasonably well and able to carry out daily activities, based on a standard cancer health scale rated 0 to 2 (where 0 means fully active and 2 means limited in physically strenuous activity but able to walk and do light work). - People with multiple myeloma that ha...

**Who might be able to join this trial:** - You must be 18 years of age or older. - You must be well enough to carry out daily activities to a certain level — the exact level required depends on which part (module) of the trial you are joining (confirm with trial site). - **For Modules A, B, and C:** You have been dia...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People who have been diagnosed with multiple myeloma - People who have previously received a standard treatment called BCMA CAR-T cell therapy - People whose scan (such as a PET scan or similar imag...

**Who might be able to join this trial:** - People who are over 18 years old - People who have been confirmed to have multiple myeloma (but not the slow-growing "smoldering" type, and not plasma cell leukemia), without significant organ damage from a related condition called amyloidosis - People whose multiple myeloma...

**Who might be able to join this trial:** - People who have been diagnosed with MGUS (Monoclonal Gammopathy of Undetermined Significance) or SMM (Smoldering Multiple Myeloma), confirmed using established international diagnostic guidelines. - People whose diagnosis has been confirmed through blood or urine tests, bone...

**Who might be able to join this trial:** - You are 18 years of age or older - You have been diagnosed with multiple myeloma that can be measured through specific blood, urine, or bone marrow tests - You have received at least two previous rounds of cancer treatment - You have previously been treated with three specif...

**Who might be able to join this trial:** - People who have multiple myeloma that has come back or stopped responding to treatment, and whose disease got worse during or after their most recent myeloma treatment. - People in the dose-finding part (Part 1) whose myeloma no longer responds to, who cannot tolerate, or wh...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with multiple myeloma and/or plasma cell leukemia (confirmed by tissue testing) and are scheduled to receive an autologous stem cell transplant (a transplant using their own stem cells), and whose doctor considers them...

**Who might be able to join this trial:** - People who are currently taking daratumumab (either alone or combined with other study treatments) or other study treatments in a qualifying Janssen research study for multiple myeloma or smoldering multiple myeloma, where that study has reached its final analysis stage, and...

Who might be able to join this trial: **Patients:** - Adults aged 18 or older - People who have been diagnosed with one of the following blood cancers or related conditions: high-risk myelodysplastic syndrome (MDS) or a related overlap condition, acute myeloid leukemia (AML) in people aged 80 or older, or those receiv...

**Who might be able to join this trial:** - Adults aged 18 or older - People diagnosed with high-risk smoldering multiple myeloma (SMM), defined by specific lab and bone marrow results that meet one of two sets of criteria used to identify those at higher risk of the condition progressing (confirm exact criteria with...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (a type of blood cancer) - People who are considered suitable for a stem cell transplant and whose disease is currently in first remission (meaning the cancer has responded to initial treatment for the first time) - People who...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (a type of blood cancer) according to standard medical guidelines, and at diagnosis had certain markers in your blood or bone marrow, plus at least one complication such as low red blood cells (anemia), reduced kidney function, h...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma that has been confirmed by laboratory testing, and whose myeloma has come back or stopped responding after at least 3 different lines of treatment — including one from each of these three types: an immunomodulatory drug, a...

Who might be able to join this trial: - People who are 50 years of age or older. - People who have been diagnosed with a blood cancer or related condition confirmed by a biopsy, including Multiple Myeloma, AL Amyloidosis, Waldenström's Macroglobulinemia, Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Myelodysplastic Syndromes...

**Who might be able to join this trial:** - People who are willing and able to follow the study requirements, in the opinion of the study doctor - People who are able to understand what the study involves - People who have given written consent to take part voluntarily, with the understanding that they may withdraw at...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma, confirmed using standard diagnostic guidelines within the past 28 days - Your myeloma can be measured through blood or urine tests showing certain levels of abnormal proteins (confirm with trial site for specific values) - You h...

**Who might be able to join this trial:** - People who are 18 years of age or older, of any gender. - People who have previously been treated with at least three different myeloma drugs — specifically including a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-CD38 antibody — and whose myeloma...

Who might be able to join this trial: - People who are 65 years of age or older and have been diagnosed with multiple myeloma according to established international diagnostic standards, with measurable levels of the disease detectable through blood or urine tests at the screening stage. - People whose general physical...

**Who might be able to join this trial:** - Adults over 18 years of age. - People who have been diagnosed with Multiple Myeloma (a type of blood cancer affecting plasma cells in the bone marrow), confirmed by bone marrow testing or a tissue biopsy, and whose disease meets at least one specific marker of severity — suc...

**Who might be able to join this trial:** - People who are willing to volunteer, have been fully informed about the trial, and have signed a consent form agreeing to complete all trial procedures. - People aged 18 to 75 years old (any gender). - People whose life expectancy is more than 12 weeks. - People who have bee...

Who might be able to join this trial: - People aged 18 years or older - People who have a confirmed diagnosis of smouldering multiple myeloma (SMM), a pre-cancer blood condition, based on specific laboratory findings showing abnormal protein levels or abnormal bone marrow plasma cell levels within a defined range - Peo...

**Who might be able to join this trial:** - People who are willing and able to follow all study requirements, including visits, treatments, and lab tests, and who have signed a consent form agreeing to take part - People who have been diagnosed with lymphoma, leukemia, or myeloma that has come back or has not responde...

**Who might be able to join this trial:** - Adults between 18 and 65 years old who are considered suitable candidates for a stem cell transplant - People diagnosed with very high-risk multiple myeloma whose disease either did not respond well enough, or stopped responding, to a standard first-line treatment regimen (V...

**Who might be able to join this trial:** - People who have been diagnosed with myeloma (a type of blood cancer) and have already completed a standard first-line treatment to reduce the cancer. People who needed extra treatment because their myeloma did not respond initially may also be considered. - People whose doct...

Who might be able to join this trial: - People who have been diagnosed with MGUS (Monoclonal Gammopathy of Undetermined Significance) or SMM (Smoldering Multiple Myeloma). - People with a non-light chain type of MGUS or SMM where certain protein levels in the blood or bone marrow meet specific thresholds (confirm with...

Who might be able to join this trial: - People who have been diagnosed with Multiple Myeloma (a type of blood cancer affecting plasma cells in the bone marrow) - People who are scheduled to have an autologous stem cell transplant (a procedure using the patient's own stem cells) at UAB within 10 weeks of joining the stu...

**Who might be able to join this trial:** - People aged 18 or older at the time of the screening visit - People with a confirmed diagnosis of B-cell chronic lymphocytic leukaemia (CLL) at an intermediate or high stage, as defined by recognised international criteria - People with a confirmed diagnosis of multiple myel...

Who might be able to join this trial: - Adults aged 18 years or older. - People who are able to complete surveys in English, or with the help of an interpreter. - People who have been diagnosed with a blood cancer (such as leukemia, lymphoma, or myeloma). - People who are receiving a specific type of cell-based treatme...

**Who might be able to join this trial:** - People who have measurable multiple myeloma disease that can be tracked during the trial, as defined by the trial's guidelines. - People whose overall health and ability to carry out daily activities meets the trial's requirements — scored as 2 or below on a standard cancer...

**Who might be able to join this trial:** - You must be 18 years of age or older - You must be relatively healthy and active in daily life, with only minor limitations from your condition (confirm with trial site for what this means in your case) - You must have been diagnosed with multiple myeloma according to standa...

Who might be able to join this trial: **For people with relapsed or refractory multiple myeloma:** - People who have an official diagnosis of multiple myeloma based on recognised international diagnostic guidelines - People whose myeloma has come back or stopped responding to treatment, and who have previously been tr...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma that has not yet been treated, where the myeloma is causing symptoms and has been confirmed by bone marrow or tissue tests, along with at least one sign of organ or tissue damage (such as high blood calcium, reduced...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma and have had blood (serum) samples tested using specific protein analysis methods - Healthy individuals with no obvious illness and a normal health check report, who have not had major long-term conditions such as high blood pr...

Who might be able to join this trial: - People aged 18 to 70 years old (inclusive) - People who have a general health/activity level score (called an ECOG score) of 0 to 2 at the start of screening, and again just before treatment begins — this scale measures how much a person's illness affects their daily activities -...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with multiple myeloma, referred to the Dana-Farber Cancer Institute (DFCI) transplant team, and placed on the waiting list for their first autologous stem cell transplant - People who are planning to receive an autolog...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma that is causing symptoms and has certain high-risk genetic features (confirm with trial site for specific features) - You are between 18 and 80 years old - You are able to carry out basic daily activities, even if you have some l...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, and where the disease can still be detected and measured by standard tests. - People who have already been through at least 3 previous rounds of treatment for multiple...

Who might be able to join this trial: - People who have been diagnosed with Multiple Myeloma (a type of blood cancer) - People who are scheduled to have their first Autologous Stem Cell Transplant (a procedure using the patient's own stem cells) - People who are 21 years of age or older - People who are able to give th...

**Who might be able to join this trial:** - People aged 18 to 75 years old, of any gender. - People who have already been treated with at least 3 different previous treatment plans for their condition, including treatments from two specific drug groups (proteasome inhibitors and immunomodulatory agents). - People whos...

**Who might be able to join this trial:** - Adults aged 18 to 72 who have been newly diagnosed with symptomatic multiple myeloma, where the disease can be measured through specific blood, urine, or imaging tests at the time of diagnosis. - People whose myeloma is considered high-risk, based on specific disease staging...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People whose doctors estimate they have a life expectancy of more than three months. - People who are well enough to carry out basic daily activities, as measured by a standard cancer performance scale (a score of 0, 1, or 2 on the...

**Who might be able to join this trial:** - People aged 0 to 75 years who are functioning well enough day-to-day, measured by a standard performance score (Karnofsky score of 70% or higher for those 16 and older, or Lansky score of 50% or higher for those under 16). - People who have a suitable matched bone marrow don...

**Who might be able to join this trial:** - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard cancer health scale (called ECOG status 0, 1, or 2) - People who have been formally diagnosed with symptomatic Multiple Myeloma (MM) according to...

Who might be able to join this trial: - People aged 30 or older who have at least one parent, sibling, or child who has been diagnosed with a blood-related condition such as MGUS, smouldering myeloma, multiple myeloma, Waldenström's Macroglobulinemia, or another blood cancer. - People aged 18 or older who have two or m...

**Who might be able to join this trial:** - Adults aged 18 or older (male or female) - People who have a specific gene mutation (called a RAS/KRAS/NRAS mutation at codon 12 or 13) found in bone marrow testing using a particular panel called VariantPlex Myeloid Panel - People who have been diagnosed with high-risk smol...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of registration. - People who have had a full health history review and physical examination within the 28 days before registration. - People with a general health status that allows them to carry out some daily activities (confirm with tr...

**Who might be able to join this trial:** - Adults aged 18 or older - People whose general health and ability to carry out daily activities falls within an acceptable range, as measured by a standard oncology scale (ECOG score of 0, 1, or 2) - People with a confirmed diagnosis of multiple myeloma, based on tissue or c...

**Who might be able to join this trial:** - You are 18 years of age or older at the time you give your consent to participate - You are in generally good physical condition and able to carry out daily activities with little or no limitation (confirm with trial site) - You have been formally diagnosed with multiple myel...

**Who might be able to join this trial:** - People who are 18 years of age or older. - People whose general health and ability to carry out daily activities meets a certain level of functioning (confirm with trial site). - People who are willing and able to sign a consent form agreeing to take part. - People who have...

**Who might be able to join this trial:** - People aged 18 or older. - People who have been diagnosed with multiple myeloma and have only received one line of treatment (this includes induction therapy, consolidation therapy, a stem cell transplant, and maintenance — all counted together as one line; switching from one...

**Who might be able to join this trial:** - People who are able and willing to give their consent to participate, or who have a legally authorised representative who can give consent on their behalf. - People who have been diagnosed with multiple myeloma (MM) that requires whole-body (systemic) treatment, according to...

**Who might be able to join this trial:** - People aged between 18 and 85 years. - People who have a blood cancer that has been confirmed by laboratory testing and falls under a recognised classification system, and for which an FDA-approved CAR T-cell therapy product is commercially available. - People whose blood ca...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma, confirmed through a laboratory test of tissue or cell samples, using recognised international diagnostic standards - People who have at least one area of myeloma activity detected on a specialised imaging scan (PET/CT or...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (confirmed by lab testing) that has gotten worse during or within 60 days of finishing their last treatment, and who have received between 1 and 3 previous treatment regimens, including at least one that contained the drug len...

**Who might be able to join this trial:** - People aged 18 to 75 years old - People who have been diagnosed with Multiple Myeloma (a type of blood cancer) according to established international guidelines - People who are newly diagnosed and whose Multiple Myeloma has spread outside the bone marrow to form tumours (ca...

**Who might be able to join this trial:** - People aged 18 or older - People whose general health and ability to carry out daily activities meets a certain minimum level, as assessed by their doctor (confirm with trial site) - People with a life expectancy of at least 3 months - People who are willing and able to foll...

Who might be able to join this trial: - People who are scheduled to receive a type of preparatory chemotherapy (called lymphodepleting chemotherapy) before a commercially available CAR-T cell therapy, for the treatment of multiple myeloma, leukemia, or lymphoma - People whose bone marrow is functioning well enough to r...

**Who might be able to join this trial:** - People aged 18 to 75 years, of any gender - People who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, based on recognised international diagnostic standards, after receiving at least 3 rounds of treatment (including at least...

**Who might be able to join this trial:** - People who have given written consent to take part voluntarily, with the understanding that consent can be withdrawn at any time. - People aged 18 years or older. - People who are well enough to carry out basic daily activities (based on a standard health performance scale,...

**Who might be able to join this trial:** - Adults aged 18 or older who are able to give written consent to participate. - People who started a treatment called teclistamab (first full dose) between 6 and 9 months before joining the trial, and who have been receiving an average dose of at least 1.5 mg/kg per month sin...

"Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (a type of blood cancer affecting plasma cells) - People who are receiving a treatment called Teclistamab - People who have signed a consent form agreeing to take part in the trial Who may not be able to join: - People who ar...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been diagnosed with multiple myeloma (MM), as confirmed by their treating doctor at the study site — people who also have a related condition called AL amyloidosis are still eligible - People who have started at least a se...

**Who might be able to join this trial:** - People aged 18 or older - People who have a close blood relative (such as a parent, child, or biological sibling) who has been diagnosed with multiple myeloma according to international diagnostic standards - People who understand what the trial involves and are willing to ta...

Who might be able to join this trial: - People who have been diagnosed with, or are suspected to have, myeloma or a related plasma cell disorder - People who are already scheduled to have a blood or bone marrow sample taken for diagnosis, monitoring, or follow-up purposes, whether before, during, or after myeloma treat...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma and are receiving initial treatment to prepare for a stem cell transplant using your own stem cells - You are willing and able to follow all birth control requirements during the trial - You are generally able to carry out daily a...

**Who might be able to join this trial:** - People who are 18 years of age or older (or the minimum legal age required in the country where the trial is taking place) at the time of signing the consent form - People who have been formally diagnosed with multiple myeloma (MM) according to established international diag...

**Who might be able to join this trial:** - People aged 18 to 75 years old - People who have been diagnosed with primary plasma cell leukemia, confirmed using internationally recognised diagnostic standards (a specific type of blood cancer where abnormal plasma cells are found circulating in the blood above certain le...

Who might be able to join this trial: - People who have had a biopsy confirming a plasma cell tumour (a type of blood cancer affecting bone marrow) with a bone lesion that can be treated with radiation therapy - People aged between 18 and 85 years old - People whose general health and ability to carry out daily activit...

**Who might be able to join this trial:** - The patient, or their legal guardian, is willing to participate and sign a consent form - Age is between 18 and 75 years old - A confirmed diagnosis of Multiple Myeloma (a type of blood cancer) according to international diagnostic standards - Certain measurable signs of the...

**Who might be able to join this trial:** - People who are 18 years of age or older at the time of signing the consent form. - People who have multiple myeloma (MM) that has come back after previous treatment, as defined by international medical guidelines. - People whose myeloma can be measured through specific blood...

Who might be able to join this trial: - People who are 18 years of age or older - People who have been newly diagnosed with active multiple myeloma (a type of blood cancer), confirmed using standard international diagnostic criteria - People who have not yet started their first treatment for multiple myeloma at the tim...

Who might be able to join this trial: - People aged between 18 and 70 years old - People who have been diagnosed with multiple myeloma (a type of blood cancer) confirmed through a bone marrow test - People who are planned to be treated in hospital with a combination therapy called RVd (a standard drug treatment for mul...

**Who might be able to join this trial:** - People who have been diagnosed with active multiple myeloma and have a specific genetic marker called t(11;14), confirmed through a special bone marrow test run under an approved testing program — the bone marrow sample must be tested within 72 hours of collection - People i...

**Who might be able to join this trial:** - People who are willing to take part voluntarily, understand what the trial involves, and are able to sign a consent form agreeing to complete all trial procedures. - People aged 18 or older, of any gender. - People whose doctors expect them to live for more than 12 weeks. -...

**Who might be able to join this trial:** - People who have given written consent to participate (or whose legal representative has done so on their behalf) - People aged 18 or older - People whose overall health and ability to carry out daily activities meets a certain level of functioning, as measured by a standard...

**Who might be able to join this trial:** - People who are willing to follow the treatment plan and visit schedule, and who agree to sign a consent form - People who are 18 years of age or older at the time of signing the consent form - People whose general physical functioning is rated at a level showing they are ful...

**Who might be able to join this trial:** - You must be able to give your agreement to take part in the study after being informed about it - Your own doctor must agree for you to take part - You must be able to read and complete surveys in English or Spanish (other languages may be accepted — confirm with trial site)...

**Who might be able to join this trial:** - People who have previously been diagnosed with MGUS or smoldering myeloma, with that diagnosis documented in a clinic note from their local oncologist within the past 6 months. - People aged 18 or older. - People who are willing to follow all study-related procedures. - Peop...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma, and a tumor sample has tested positive for a specific protein called NY-ESO-1 - You have a specific genetic marker on your immune cells called HLA-A\*02:01, HLA-A\*02:05, or HLA-A\*02:06 (found through a blood test) - Your multi...

Who might be able to join this trial: - People who are attending Zhujiang Hospital, whether as an outpatient, emergency, or inpatient - People who are 18 years of age or older - People who have enough remaining serum (blood) samples available and have signed a broad informed consent form Who may not be able to join: -...

**Who might be able to join this trial:** **For people with kidney damage caused by multiple myeloma (cast nephropathy):** - People who have been diagnosed with newly diagnosed multiple myeloma (MM) according to standard international guidelines - People whose myeloma can be measured through blood or urine tests, with...

**Who might be able to join this trial:** - You are willing to take part and have given your written agreement to join the study - You are between 18 and 75 years old (any gender) - Your doctor estimates you are likely to live for at least 12 weeks - You are reasonably active and able to care for yourself, with limite...

**Who might be able to join this trial:** - Adults aged 18 or older at the time of giving consent to participate. - People who are not eligible to receive an autologous stem cell transplant (a procedure where a person's own stem cells are collected and returned after high-dose treatment). - People who have tested nega...

**Who might be able to join this trial:** - You are a man or woman aged 65 or older who either cannot receive a stem cell transplant or does not plan to have one right away - You have been diagnosed with multiple myeloma, confirmed by a bone marrow test showing at least 10% abnormal plasma cells, or a biopsy confirmin...

**Who might be able to join this trial:** - People who have been confirmed, through laboratory testing of tissue or cells, to have smoldering multiple myeloma (SMM) — a condition where abnormal plasma cells are present in the bone marrow but have not yet caused serious organ damage — meeting specific blood, urine, and...

**Who might be able to join this trial:** - People who have been formally diagnosed with multiple myeloma (a type of blood cancer) according to standard international diagnostic guidelines, and who at the time of diagnosis had certain measurable levels of abnormal protein in their blood or bone marrow, along with at l...

**Who might be able to join this trial:** - People who were diagnosed with multiple myeloma confirmed by a tissue or cell sample, where the diagnosis included abnormal plasma cells making up at least 10% of bone marrow cells, an abnormal protein in the blood or urine, and signs of organ damage or other specific diseas...

**Who might be able to join this trial:** - People diagnosed with multiple myeloma who have previously received induction treatment that included the drug daratumumab (for at least 3 cycles) and whose disease responded at least partially to that treatment. - People who completed an autologous stem cell transplant (a p...

Who might be able to join this trial: - People who are at least 18 years old. - People who have been newly diagnosed with symptomatic multiple myeloma, confirmed using internationally recognised diagnostic guidelines from 2014. - People whose multiple myeloma has shown at least a partial response to one previous treatm...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (a type of blood cancer affecting plasma cells in the bone marrow), confirmed by standard medical tests - Your myeloma is currently active and measurable through blood or urine tests showing abnormal protein levels - Your myeloma...

Who might be able to join this trial: - People with multiple myeloma (MM) who have a confirmed diagnosis, need treatment, and whose disease has come back or stopped responding after at least 3 previous rounds of treatment. - People with non-Hodgkin's lymphoma (NHL) whose disease has come back or stopped responding afte...

Who might be able to join this trial: - People who have multiple myeloma that has come back or stopped responding to treatment, and who have previously received a certain number of treatment regimens (the exact number required depends on which part of the trial a person is being considered for — confirm with trial site...

**Who might be able to join this trial:** - People between 18 and 70 years old - People expected to live for more than 12 weeks - People who have been diagnosed with multiple myeloma through physical checks, lab tests, pathology, and imaging scans - People whose multiple myeloma has not responded to treatment (refract...

**Who might be able to join this trial:** - Adults aged 18 or older (any gender) - People diagnosed with aggressive non-Hodgkin's lymphoma or multiple myeloma who are planned to receive, or have started no more than two cycles of, chemotherapy — or people with myeloma or lymphoma who need more intensive treatment suppo...

**Who might be able to join this trial:** - People who are willing to give written consent to take part and understand they are free to withdraw at any time without affecting their future care. - People aged 18 years or older, of any gender. - People with a performance status score of 0 or 1 on the ECOG scale, meaning...

**Who might be able to join this trial:** - You have been diagnosed with either high-risk MGUS (an early blood condition where abnormal proteins are found) or a lower-risk form of smoldering multiple myeloma (a pre-cancer condition with no symptoms yet), as defined by the trial guidelines - You are generally able to ca...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma (MM), have had at least one round of treatment in the past, and are currently on a maintenance treatment plan using specific types of cancer medication (a proteasome inhibitor, an immunomodulatory agent, or an anti-CD38 antibod...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (using the specific medical code C90.00), where the diagnosis was confirmed by a medical professional reviewing their records, and occurred after the formal launch of the MRD-targeted clinical pathway in the Exigent networ...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma that has come back (relapsed) or stopped responding to treatment (refractory). - People whose myeloma showed signs of getting worse either during or within 12 months of finishing their most recent myeloma treatment (measured fr...

**Who might be able to join this trial:** - You are willing to sign a consent form agreeing to take part in the study. - You are aged 18 or older but under 70 years old. - You have been newly diagnosed with multiple myeloma, and your disease can be measured through specific blood, urine, or protein tests that meet cer...

**Who might be able to join this trial:** - People aged 18 or older - People who have been diagnosed with multiple myeloma, confirmed by a bone marrow test showing at least 10% abnormal plasma cells, along with measurable levels of the abnormal protein the disease produces (detectable in blood or urine tests) - People...

**Who might be able to join this trial:** - People who have been diagnosed with relapsed or refractory multiple myeloma (myeloma that has come back or stopped responding to treatment) according to recognised international guidelines. - People whose doctors expect them to survive for more than 12 weeks. - People who ar...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma and are not able to have a stem cell transplant. - People whose disease was measurable at the time of diagnosis, shown by specific levels of certain proteins in the blood or urine (confirm with trial site for exact m...

**Who might be able to join this trial:** - People who are older than 18 years of age - People who have been diagnosed with smoldering multiple myeloma (a pre-active stage of a blood cell condition) for 5 years or less, with detectable levels of an abnormal protein in their blood or urine - People whose bone marrow co...

**Who might be able to join this trial:** - You have multiple myeloma that has come back or stopped responding to treatment, and you have already tried at least 3 different types of treatment, including specific drug types targeting myeloma in different ways (such as bortezomib or carfilzomib, daratumumab, and a BCMA-...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (a type of blood cancer) based on standard international diagnostic criteria, with measurable signs of the disease at the time of diagnosis. - People aged 18 or older. - People who have completed 12 cycles (or up to 13 cyc...

**Who might be able to join this trial:** - You are between 18 and 70 years old. - Doctors expect you to live for more than 12 weeks. - You have been diagnosed with multiple myeloma confirmed through physical checks, lab tests, tissue samples, and scans. - Your multiple myeloma has stopped responding to treatment (ref...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma and are considered suitable candidates for a stem cell transplant. - People whose multiple myeloma is classified as "high-risk," meaning certain specific genetic changes have been found in their cancer cells. - Peopl...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (MM) based on specific medical criteria, such as abnormal protein levels in the blood or urine, or abnormal plasma cell counts in the bone marrow (confirm with trial site for exact diagnostic details) - People whose multip...

Who might be able to join this trial: - People who were previously enrolled and treated in a specific trial called GMMG-HD8 / DSMM XIX, OR people who received a four-drug treatment for myeloma that included a proteasome inhibitor (such as bortezomib), an immunomodulatory drug (such as thalidomide or lenalidomide), dexa...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma (MM) based on standard medical criteria, including having a certain level of abnormal plasma cells in the bone marrow or a proven tumour made of plasma cells - People whose myeloma has been confirmed as "active," meaning i...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, based on recognised international criteria (such as a significant rise in certain protein levels in the blood or urine, or the development of new tumours or high calcium le...

**Who might be able to join this trial:** - People who have been diagnosed with active multiple myeloma, confirmed by specific blood or urine test results showing measurable levels of abnormal proteins (confirm with trial site for exact thresholds). - People who have already gone through at least 3 previous rounds (li...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma that came back for the first time after having a stem cell transplant using your own stem cells (called an autologous stem cell transplant, or ASCT). - You received a second autologous stem cell transplant (using your own stem cel...

**Who might be able to join this trial:** - People diagnosed with high-risk multiple myeloma (identified by specific genetic markers — del17p, t(4;14), t(14;16), or 1q21 — found through a FISH test) or multiple myeloma that has spread outside the bone marrow. - People between 18 and 70 years old (inclusive), of any ge...

**Who might be able to join this trial:** - You are male or female and are 70 years of age or older - You have been diagnosed with multiple myeloma (a type of blood cancer) - You are well enough to carry out some or all of your daily activities (ranging from fully active to limited self-care ability) - You are about to...

**Who might be able to join this trial:** **For patients with multiple myeloma (Part 1):** - Adults aged 18 or older who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, and whose cancer has worsened on the most recent treatment — where the treating doctor determines th...

**Who might be able to join this trial:** - People aged 18 or older, of any gender - People who have been diagnosed with active, symptomatic multiple myeloma (based on established 2014 diagnostic guidelines) and have measurable signs of the disease - People who are experiencing their first relapse of multiple myeloma...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, with up to 5 bone lesions that can be treated with radiation therapy, and whose bone lesions score within a certain safety range for spinal stability...

**Who might be able to join this trial:** - People who are able to give their signed agreement to participate in the trial - People aged 18 to 75 years old at the time of screening - People whose life expectancy is more than 12 weeks - People who have been diagnosed with multiple myeloma (MM) according to recognised in...

Who might be able to join this trial: - People who have been diagnosed with Multiple Myeloma - People whose medical team has determined they are suitable for a stem cell transplant using their own cells, or those who are not suitable for this type of transplant - People who are receiving chemotherapy before or after a...

Who might be able to join this trial: - People who have a confirmed diagnosis of multiple myeloma (a type of blood cancer) - People who received their first dose of teclistamab on or before 31 December 2022 (REALiTEC Cohort 1), OR between 1 January 2023 and 31 December 2024 (REALiTEC Cohort 2), OR between 1 January 202...

Who might be able to join this trial: - People who have been diagnosed with a specific type of amyloidosis called AL amyloidosis, confirmed according to the trial's guidelines - People whose disease can be measured through a specific blood test that looks at proteins called free light chains - People who have already r...

**Who might be able to join this trial:** - People who have signed a consent form agreeing to take part in the study. - People aged 18 or older at the time of signing the consent form. - People with a confirmed diagnosis of multiple myeloma, diagnosed using standard international criteria. - People whose myeloma can b...

Who might be able to join this trial: - People who are willing to give consent (written or verbal) to take part in the study and allow their personal health information to be used. - People who are able and willing to follow the study procedures, as assessed by the study doctor. - People who are 60 years of age or olde...

Who might be able to join this trial: - People who are 18 years of age or older at the time of registration - People who have been diagnosed with relapsed Multiple Myeloma (myeloma that has come back after treatment), based on recognised international diagnostic standards - People whose treating doctor agrees to take p...

Who might be able to join this trial: - People who have been diagnosed with cholangiocarcinoma (a type of bile duct cancer), multiple myeloma (a blood cancer), or colon or rectal cancer that was diagnosed at an early age - People diagnosed with multiple myeloma who identify as African-American - People diagnosed with c...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have previously been diagnosed with multiple myeloma and whose disease has come back or stopped responding to treatment - For the first phase of the trial (dose escalation): people who have already received at least 3 prior rounds of trea...

**Who might be able to join this trial:** - People who have been formally diagnosed with multiple myeloma (MM). - People whose multiple myeloma can be measured through specific blood or urine tests showing certain levels of disease markers. - People whose multiple myeloma has come back or stopped responding to treatme...

**Who might be able to join this trial:** - People who have previously received a commercially available gene-modified cell therapy made by Bristol-Myers Squibb (BMS), and who have since been diagnosed with a specific type of new, separate cancer that BMS has identified as qualifying for this study. - People who recei...

**Who might be able to join this trial:** - People who are 40 years of age or older - People who have been diagnosed with either Smoldering Multiple Myeloma or a Monoclonal Gammopathy (two conditions involving abnormal proteins in the blood) - People whose dFLC level (a measurement of certain proteins in the blood cal...

**Who might be able to join this trial:** - You are willing to take part and have signed a consent form agreeing to participate. - You are 18 years of age or older. - You have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, and all standard treatment options have already bee...

**Who might be able to join this trial:** - You have been newly diagnosed with multiple myeloma (a type of blood cancer), confirmed before any treatment began. - You have already received a combination of three or four drugs to treat your myeloma, including at least two from these groups: immunomodulatory drugs (IMiDs...

Who might be able to join this trial: **Part A** - People who have been diagnosed with MGUS (a condition where abnormal proteins are found in the blood) with an abnormal result on a specific blood test called the free light chain ratio, or who have smouldering multiple myeloma (an early, symptom-free form of multiple...

**Who might be able to join this trial:** - You are between 18 and 90 years old, your doctor suspects you may have multiple myeloma, and you are scheduled to have a bone marrow or tissue sample taken within the next 3 months - You are over 18 years old and have already been diagnosed with active multiple myeloma - You...

**Who might be able to join this trial:** - People who are willing to take part voluntarily, have been fully informed about the study, and have signed a consent form agreeing to follow all trial procedures - Adults aged 18 or older, of any gender - People who have been newly diagnosed with multiple myeloma, according...

Who might be able to join this trial: - People who have been newly diagnosed with multiple myeloma (those who have received up to one cycle of a bortezomib-based treatment for urgent reasons such as bone pain, kidney problems, or high calcium levels may still be considered) - People aged 18 or older - People whose dise...

**Who might be able to join this trial:** - You must be an adult (18 or older) - You must be staying in a protected (isolation) unit in a blood cancer (hematology) department for one of the following treatments: initial chemotherapy for acute myeloid leukemia or acute lymphoblastic leukemia, intensive chemotherapy with...

**Who might be able to join this trial:** - People who have multiple myeloma that has come back after treatment, or that stopped responding to treatment — either during treatment or within 60 days of finishing it. - People whose disease can be measured by specific blood or urine tests, with results taken within 28 day...

"Who might be able to join this trial: - People diagnosed with multiple myeloma or plasmacytoma (types of blood/bone marrow cancer) - People whose treatment goal is achieving a strictly complete remission (meaning all signs of cancer are gone by very thorough testing) - People whose doctors expect them to live for more...

**Who might be able to join this trial:** - People who have a confirmed diagnosis of multiple myeloma. - People whose multiple myeloma has come back or stopped responding to 3 or more previous treatments, where those treatments included at least one drug from each of these three groups: immunomodulatory drugs, proteaso...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma or plasmacytoma (types of blood cancer) - People whose cancer has responded very well or completely to previous combination treatments - People whose doctors expect them to survive for more than 12 weeks - People who have suita...

**Who might be able to join this trial:** - People who have been confirmed as having symptomatic multiple myeloma (an active form of blood cancer affecting plasma cells) according to established international diagnostic standards. - People whose myeloma was measurable at the time of diagnosis — meaning a certain level...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma, based on internationally recognised diagnostic guidelines - People between 18 and 70 years of age - People whose myeloma showed a very strong response to 4–6 rounds of initial treatment, including reaching a level w...

Who might be able to join this trial: - People aged 18 to 75 years of any gender. - People who have previously been diagnosed with multiple myeloma and have received 1 to 2 rounds of treatment (including treatments based on proteasome inhibitors and immunomodulatory drugs), where each round included at least one full c...

Who might be able to join this trial: - People who have been diagnosed with multiple myeloma, confirmed through a tissue or cell sample test. - People who have had a stem cell transplant using their own cells (autologous) must have had that transplant more than 100 days before joining the study. - People whose myeloma...

Who might be able to join this trial: - People aged 18 years or older - People who have agreed to take part and signed a consent form - People who are covered by a social security (health insurance) scheme - **Group 1:** People who have been newly diagnosed with multiple myeloma (a type of blood cancer) and whose docto...

**Who might be able to join this trial:** - People aged 18 years or older - People who are willing and able to provide written consent to participate - People who have been diagnosed with multiple myeloma that has come back (relapsed) and is no longer responding to treatment (refractory) - People who have already recei...

Who might be able to join this trial: - People who are at least 18 years old - People who are able to understand and willing to sign a consent form (a legal representative may sign on their behalf if needed) - People who have been diagnosed with a specific type of multiple myeloma (called IgG or IgA multiple myeloma) a...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form - People whose general health and ability to carry out daily activities is rated as 0 or 1 on a standard oncology scale (meaning fully active or restricted in strenuous activity only) - People who hav...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma according to Chinese medical guidelines (2022 version). - People who have already received at least one prior treatment for multiple myeloma that included both lenalidomide and a proteasome inhibitor, and whose disease has...

**Who might be able to join this trial:** *Patients:* - Adults aged 18 or older - People who have been newly diagnosed with multiple myeloma, whose multiple myeloma or aggressive B cell lymphoma has come back or stopped responding to treatment, or who need a change in their treatment plan - People whose general physic...

Who might be able to join this trial: **For patients:** - People who have a blood cancer that has come back or stopped responding to treatment - People who are 18 years of age or older - People who receive their main cancer care at Dana-Farber Cancer Institute (DFCI), with at least 2 outpatient visits there in the 12...

**Who might be able to join this trial:** - People aged 65 years or older - People who have been newly diagnosed with multiple myeloma that meets specific international diagnostic standards, including having a measurable amount of the disease detected through blood or urine tests - People whose multiple myeloma has ca...

**Who might be able to join this trial:** - You have been diagnosed with a blood cancer called multiple myeloma, confirmed using standard medical guidelines - You have previously been treated with three specific types of cancer drugs: a proteasome inhibitor (PI), an immunomodulatory drug (IMiD), and an anti-CD38 antib...

**Who might be able to join this trial:** - The patient or their legal guardian is willing to participate and sign a consent form. - Aged between 18 and 75 years old. - Has been diagnosed with Multiple Myeloma (MM) according to international diagnostic standards (IMWG 2014). - Has relapsed (disease came back within 60...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma (MM) confirmed according to recognised international guidelines. - You are newly diagnosed with multiple myeloma and your doctors consider you suitable for high-dose chemotherapy and a stem cell transplant. - You are generally ab...

**Who might be able to join this trial:** - You are 18 years of age or older - You have a type of T-cell lymphoma (specifically peripheral T-cell lymphoma-NOS, anaplastic large cell lymphoma, or mycosis fungoides) that has come back or stopped responding to previous treatment (this applies to Group E of the trial) - Y...

**Who might be able to join this trial:** - People who are able to understand and sign a consent form agreeing to take part in the study. - People aged between 18 and 75 years old (inclusive). - People whose general physical functioning falls within an acceptable range, as measured by a standard medical scoring system...

**Who might be able to join this trial:** - People who have signed a consent form before entering the study - People aged between 18 and 78 years old - People who have been diagnosed with active multiple myeloma, as defined by international myeloma guidelines - People who have waited at least 7 days since their last d...

**Who might be able to join this trial:** - Adults aged 18 or older - People who have been diagnosed with multiple myeloma - People who are able to complete monthly questionnaires in Hebrew, Arabic, or Russian - People who are willing and able to sign a consent form agreeing to take part **Who may not be able to join:...

**Who might be able to join this trial:** - You understand the study and are willing to sign a consent form, attend follow-up visits, and complete all required steps - You are between 18 and 75 years old (any gender) - You have been officially diagnosed with Multiple Myeloma (MM) according to international standards -...

**Who might be able to join this trial:** - Adults aged 18 or older, of any gender. - People who have been diagnosed with myeloma and/or Plasma Cell Leukemia (confirmed by lab testing of tissue), who are newly diagnosed and have completed no more than one cycle of myeloma treatment. - Women who could become pregnant m...

**Who might be able to join this trial:** - People who have previously been diagnosed with multiple myeloma (a type of blood cancer) based on standard diagnostic guidelines. - People who have been treated with at least 4 previous lines of myeloma treatment, including three specific types of therapy: an immunomodulatin...

**Who might be able to join this trial:** - People who have been newly diagnosed with multiple myeloma - People whose doctors have determined that a stem cell transplant (using their own stem cells) is an appropriate treatment for them - People who are either fully active or have only minor limitations in daily physica...

**Who might be able to join this trial:** - People who have been confirmed with a diagnosis of multiple myeloma according to established international guidelines (IMWG criteria). - People whose multiple myeloma is currently in a first complete response (full or stringent), or has partially responded or responded very...

**Who might be able to join this trial:** - Adults aged 18 or older who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment, confirmed using standard international criteria. - People who have already received at least three rounds of treatment, including specific drug types...

Who might be able to join this trial: - People aged 45 years or older. - People whose blood test showed no abnormal protein (called monoclonal gammaglobulin) when screened using a specific laboratory method called MALDI-TOF MS. - People who have no signs or symptoms of infection, and whose blood test results for infect...

**Who might be able to join this trial:** **Phase I:** - People who have multiple myeloma that has come back or stopped responding to treatment, specifically after having been treated with a combination of anti-CD38 antibody therapy and a type of drug called an immunomodulatory drug (IMiD), and who have since started...

Who might be able to join this trial: - Adults who have been diagnosed with multiple myeloma (a type of blood cancer involving abnormal plasma cells in the bone marrow, with detectable abnormal protein in the blood or urine, and signs of organ damage related to the disease). - Adults who have been diagnosed with MGUS (...

**Who might be able to join this trial:** - You are 18 years old or older - You have been diagnosed with multiple myeloma (MM) that has come back after previous treatment - You have received between 1 and 3 previous treatment plans for multiple myeloma (where each plan included at least 2 cycles of treatment) - You ar...

Who might be able to join this trial: - People who are at least 18 years old. - People who have given written consent to take part in the trial (or whose legal representative has done so). - People who agree to allow stored tumour tissue samples from their diagnosis to be used for the study (exceptions may be possible...

**Who might be able to join this trial:** - People who are 18 years of age or older (or the legal age of consent in their country) at the time of signing the consent form. - People diagnosed with high-risk smoldering multiple myeloma (a pre-cancer blood condition), meeting at least one of two specific risk definitions...

**Who might be able to join this trial:** - The participant, or their legal representative, must be willing to sign a consent form showing they understand the study and agree to take part. - A person must have a confirmed diagnosis of multiple myeloma based on standard international guidelines. - A person must have pr...

**Who might be able to join this trial:** - You are between 18 and 80 years old (any gender) - You have been diagnosed with multiple myeloma that has come back or has not responded to previous treatments - Lab or tissue tests show that your myeloma cells have a protein called BCMA on their surface - Your doctor estima...

Who might be able to join this trial: - People who have received a high-dose chemotherapy drug called melphalan (at a dose of 140–200 mg/m²) - People who have undergone an autologous stem cell transplant (a transplant using their own stem cells) Who may not be able to join: - People who have a known allergy to the med...

Who might be able to join this trial: **General criteria (all participants):** - People who, in the investigator's opinion, are able to understand and follow the study requirements - People living independently in the community or in an assisted-living facility where they are mainly responsible for their own daily car...

Who might be able to join this trial: - People who are 18 years of age or older at the time of signing the consent form. - People who have been formally diagnosed with multiple myeloma according to recognised international diagnostic guidelines. - People whose disease is measurable through blood or urine tests showing...

**Who might be able to join this trial:** - People who have been diagnosed with multiple myeloma that has come back or stopped responding to treatment (relapsed/refractory multiple myeloma) - People whose myeloma can be measured through at least one of the following: a specific protein in the blood (M-protein ≥ 0.5 g/...

**Who might be able to join this trial:** - You have been diagnosed with multiple myeloma, confirmed through a tissue test (biopsy). - Your kidneys are not working at full capacity — specifically, your kidney filtering rate (eGFR) is below 45. - You are 18 years of age or older. - You are generally able to carry out n...

**Who might be able to join this trial:** - Adults aged 18 or older - People whose general health and ability to carry out daily activities meets a standard medical score of 2 or below on a scale used to measure cancer patients' wellbeing (confirm with trial site) - People diagnosed with multiple myeloma that has retu...

Who might be able to join this trial: - You must be 18 years old or older - You must have a confirmed diagnosis of multiple myeloma (a type of blood cancer) or a type of blood/immune system cancer that has a specific marker called CD19+, diagnosed using standard medical tests - You must be willing and able to sign a co...

**Who might be able to join this trial:** - People aged 18 to 80 years (inclusive) at the time of signing the consent form - People newly diagnosed with primary plasma cell leukemia (a rare and aggressive blood cancer), confirmed according to current international diagnostic standards, including a certain percentage o...