Phase 3 Myeloma Trial, Recruiting NCT06932562 Sponsor: European Myeloma Network B.V. Condition: Myeloma
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Phase 3 Myeloma Trial, Recruiting

NCT06932562
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with symptomatic multiple myeloma, confirmed using standard international guidelines.
  • People who have been assessed as not suitable for high-dose chemotherapy followed by a stem cell transplant using their own cells.
  • People whose myeloma can be measured through standard tests, as defined by the trial.
  • People who are reasonably functional in daily life, based on a standard health performance scale (scores of 0, 1, or 2 on the ECOG scale).
  • People whose blood and other lab test results fall within the ranges required by the trial.

Who may not be able to join:

  • People who score 2 on the International Myeloma Working Group Frailty Index, unless that score is based solely on age.
  • People who are choosing to delay a stem cell transplant based on personal preference rather than medical reasons.
  • People with certain related blood or plasma cell conditions, including non-secretory myeloma, active plasma cell leukaemia, AL amyloidosis alongside a myeloma diagnosis, other forms of amyloidosis, Waldenström macroglobulinaemia, or POEMS syndrome.
  • People who have previously received treatment for early-stage or pre-myeloma conditions (MGUS or smoldering myeloma), or for myeloma itself — with the exception of targeted radiation therapy and/or a short course of steroid treatment as defined by the trial.
  • People who have received or are currently receiving any experimental treatment or cell therapy that may act against myeloma.
  • People who have myeloma involvement in the brain or spinal fluid, a history of certain neurological conditions or movement disorders, a history of a serious brain infection called PML, or a history of seizures, mini-strokes, or stroke within the 12 months before starting the trial.
  • People with serious ongoing illnesses that are not well controlled.
  • People for whom the trial medications daratumumab or lenalidomide are medically unsuitable, based on local prescribing guidelines.
  • People who have previously had a bone marrow transplant using cells from another person, or who have had a solid organ transplant at any time.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Roberto Mina, A.O.U. Città della Salute e della Scienza di Torino

Phone: +31 10 268 70 65

Australian sites

Flinders Medical Centre, Adelaide,
Box Hill Hospital, Box Hill,
Canberra Hospital, Canberra,
Barwon Health, University Hospital Geelong, Geelong,
Austin Hospital, Heidelberg,
Nepean Cancer Centre, Kingswood,
Northern Hospital, Melbourne,
Sunshine Coast Health, Sunshine Coast,

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
European Myeloma Network B.V.
Registry
ClinicalTrials.gov
Start date
23 December 2025
Est. completion
1 December 2036

Where this trial is recruiting

🇦🇺 Australia 🇦🇹 Austria 🇭🇷 Croatia 🇨🇿 Czechia 🇩🇰 Denmark 🇪🇪 Estonia 🇫🇮 Finland 🇩🇪 Germany 🇬🇷 Greece 🇮🇪 Ireland 🇮🇹 Italy 🇳🇱 Netherlands 🇳🇴 Norway 🇵🇹 Portugal 🇪🇸 Spain 🇸🇪 Sweden 🇨🇭 Switzerland Turkey (Türkiye)

8 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Minimal Residual Disease (MRD); MRD negative CR status by BICR; Progression Free Survival (PFS) per IMWG criteria; PFS as determined by BICR

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov