Phase 3 Myeloma Trial, Recruiting NCT07518186 Sponsor: Janssen Research & Development, LLC Condition: Myeloma
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Phase 3 Myeloma Trial, Recruiting

NCT07518186
Recruiting Phase 3 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been formally diagnosed with multiple myeloma (a type of blood cancer) according to international diagnostic standards, with signs of the disease that can be measured by a central laboratory at the time of screening
  • People who have already received between 1 and 3 previous treatments for their multiple myeloma, including a specific type of drug that targets a protein called CD38, and a drug called lenalidomide
  • People whose overall physical health and ability to carry out daily activities falls within an acceptable range, as measured by a standard medical scale (called the ECOG scale, scored 0 to 2) at the time of screening and just before starting the study treatment
  • People whose blood and lab test results meet specific levels set out in the study rules, checked during screening and within 1 day of starting the study treatment

Who may not be able to join:

  • People who have had major surgery (for example, surgery requiring general anaesthesia) or a serious physical injury within 2 weeks before the first dose, who have not fully recovered from surgery, or who have surgery planned during the expected period of study participation
  • People who are known or suspected to have allergies, sensitivities, intolerances, or other medical reasons that would make it unsafe to take the study drugs (JNJ-79635322 or teclistamab) or their ingredients
  • People who have any ongoing blood or bone marrow conditions other than multiple myeloma, a history of another cancer that is considered at high risk of returning and may need ongoing treatment, or another active cancer (meaning one that has been progressing or required a treatment change within the last 24 months)
  • People who have known or suspected involvement of multiple myeloma in the brain or spinal fluid, or who show clinical signs of this — unless specific brain scans and fluid tests come back negative (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 12 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Phone: 844-434-4210

Australian sites

St Vincent s Hospital Sydney, Darlinghurst,

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
31 May 2026
Est. completion
29 April 2029

Where this trial is recruiting

🇦🇺 Australia 🇮🇱 Israel 🇯🇵 Japan 🇹🇼 Taiwan Turkey (Türkiye) 🇺🇸 United States

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Complete Response (CR) or Better; Progression-Free Survival (PFS)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 12 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov