Phase 2 COPD Trial, Recruiting NCT05061368 Sponsor: University of Alberta Condition: COPD
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Phase 2 COPD Trial, Recruiting

NCT05061368
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For people with COPD:

  • A person must have a COPD diagnosis confirmed by a breathing test showing a specific airflow ratio (FEV1/FVC) below the normal lower limit after using a bronchodilator
  • A person's lung function (FEV1) must be above 30% of what is expected for someone of their age, height, and sex

For healthy comparison participants (people without COPD):

  • A person must not have a COPD diagnosis
  • A person must have a breathing test result (FEV1/FVC ratio) above the normal lower limit after using a bronchodilator
  • A person's lung function (FEV1) must be above 80% of what is expected for someone of their age, height, and sex

Who may not be able to join:

  • People who have a medical reason why exercise testing would be unsafe, or who have a bone or joint condition that could limit their ability to exercise during testing
  • People with pre-existing heart conditions — such as heart failure, a heart defect present from birth, or a heart valve problem — that could limit exercise testing
  • People who had a diagnosis of high blood pressure in the lungs (pulmonary hypertension) before their COPD diagnosis
  • People currently taking certain medications, including phosphodiesterase type-5 inhibitors, nitrates, opioids, azole antifungals, macrolide antibiotics, protease inhibitors, alpha blockers, riociguat, mifepristone, or rifamycin (confirm with trial site if unsure whether a current medication is on this list)
  • People who are pregnant or breastfeeding
  • Women who could become pregnant and are not willing to use an accepted form of contraception (such as tubal ligation, the contraceptive pill, an IUD, a diaphragm, or condoms) for the duration of the study
  • Women who have gone through menopause must have had no menstrual period for 12 months or more

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Michael K Stickland, Ph.D., University of Alberta

Phone: 7804921121

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
1 March 2022
Est. completion
1 May 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Exercise Capacity

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov