Alzheimer's Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are 60 years of age or older.
• People who have been diagnosed with mild cognitive impairment (MCI) or early-stage Alzheimer's disease (possible or probable), confirmed using standard medical definitions.
• People whose cognitive test scores fall within a specific range, indicating at least mild memory or thinking difficulties (confirmed using a standard test called the MoCA).
• People who have at least some mild depressive symptoms, as measured by a standard mood rating scale called the MADRS.
• People who are either not taking antidepressants, cholinesterase inhibitors, or memantine, or who have been on a stable dose of these medications for at least 12 weeks.
• People who have chronic pain (nerve pain, body pain, or a mix of both) that has been present on most days for at least 3 months, with an average pain level of 4 or more out of 10.
• People whose level of daily functioning and memory difficulties fall within a specific range on a standard scale called the Clinical Dementia Rating (CDR).
• People who are able to understand and agree to participate in the trial on their own.
• People who have a caregiver, family member, or close person willing to take part as a study partner.

Who may not be able to join:

• People assessed by the trial medical team as having a significant risk of suicide.
• People whose overall physical or neurological health is considered too unstable to safely take part in a research study.
• People whose mental health is considered too unstable to safely take part in a talking therapy-based trial.
• People who need to be admitted to a psychiatric hospital for safety reasons at the time of joining.
• People who are not fluent in English.

Important: Always verify eligibility with the trial site directly before applying.