Stroke Trial, Recruiting NCT05093673 Sponsor: Johns Hopkins University Condition: Stroke
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Stroke Trial, Recruiting

NCT05093673
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have had a stroke on the left side of the brain, either from a blocked blood vessel or a bleed, and whose stroke is considered long-term (chronic)
  • People who spoke English fluently before their stroke, based on their own report
  • People aged 18 or older
  • People who are at least 6 months past the date their stroke occurred
  • People who have been diagnosed with aphasia (difficulty with language) and trouble naming things, confirmed using a specific language assessment called the Western Aphasia Battery-Revised

Who may not be able to join:

  • People whose stroke or brain injury affected the right side of the cerebellum (a part of the brain at the back of the head)
  • People who have a history of any other neurological condition affecting the brain (other than stroke), any brain-degenerating condition, or any psychiatric disorder
  • People who have had seizures (fits) within the past 6 months
  • People who have vision or hearing problems that have not been corrected, based on their own report
  • People who are taking medications that are known to lower the threshold for seizures (for example, methylphenidate)
  • People who are taking a type of medication called NMDA antagonists (for example, memantine)
  • People who have had brain surgery or who have any metal in their head
  • People whose ability to understand spoken language is severely limited, based on a specific score on the Western Aphasia Battery-Revised assessment
  • People whose ability to produce spoken words is severely limited, based on a specific score on the Western Aphasia Battery-Revised assessment
  • People with severe claustrophobia (fear of enclosed spaces), those with a cardiac pacemaker or certain metal implants in the body, and people who are pregnant will not be able to take part in the MRI scanning portion of the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Rajani Sebastian, PhD, Johns Hopkins University

Phone: 410-502-2445

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
25 October 2021
Est. completion
1 September 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in accuracy of naming untrained pictures (Philadelphia Naming Test)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov