Phase 4 Vasculitis Trial, Recruiting NCT05102448 Sponsor: Shanghai Zhongshan Hospital Condition: Vasculitis
Back to Vasculitis

Phase 4 Vasculitis Trial, Recruiting

NCT05102448
Recruiting Phase 4

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Takayasu Arteritis (TAK) using recognized medical classification guidelines
  • You are a man or woman between 18 and 65 years old
  • You agree not to try to become pregnant (or father a child) during the trial, and if you are a woman, your pregnancy test must come back negative before joining
  • Your Takayasu Arteritis is currently considered active, based on a standard set of disease activity measures
  • You are willing to read and sign a consent form agreeing to take part in the trial

Who may not be able to join:

  • You have serious organ problems, such as severe heart failure, significantly reduced kidney function, moderate-to-severe liver disease, frequent fainting/blackout episodes (3 days in a row), a recent stroke or brain bleed, or blood pressure higher than 160/100 mmHg
  • You have had major blood vessel surgery related to TAK in the last 3 months, or any other blood vessel procedure or surgery (unrelated to TAK) in the last month
  • You have another autoimmune disease, such as lupus, Behcet's disease, or a related blood vessel condition
  • You have another serious, worsening, or hard-to-control illness affecting your kidneys, liver, blood, gut, lungs, or heart that could put you at extra risk
  • You have a condition like asthma that may require you to take medium-to-high doses of steroid medication during the study
  • You currently have an active infection such as hepatitis B, hepatitis C, tuberculosis, or another serious ongoing infection
  • You have or have had cancer
  • Your recent blood test results show certain abnormalities, such as raised liver enzymes, low white blood cell count, low platelets, low hemoglobin (anaemia), or other results that could put you at risk (confirm with trial site)
  • You are allergic to the study drug being tested
  • You have previously tried the medications tofacitinib or methotrexate for at least 3 months and they did not work for you

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 4 trials study a drug that has already been approved, monitoring long-term safety and effectiveness in real-world use.

Contact this trial

Principal Investigator: Lindi Jiang, Ph.D., M.D., Department of Rheumatology in Zhongshan hospital, Fudan University

Phone: 021-64041990

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 4
Registry
ClinicalTrials.gov
Start date
1 November 2021
Est. completion
31 December 2025

Where this trial is recruiting

🇨🇳 China

Primary endpoints

The effectiveness rate after 6 months' treatment

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov