Motor Neurone Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People experiencing symptoms such as arm or leg weakness, stiff or abnormal walking, muscle wasting, muscle twitching, difficulty swallowing, difficulty speaking, shortness of breath, overactive reflexes, or previous test results showing signs of muscle nerve damage (for one part of the study)
• People between 20 and 90 years of age (for one part of the study)
• People from the group above who have been classified under a specific ALS diagnostic scoring system (called the Awaji criteria, without IMC) as "Possible," "Probable," or "Definite" ALS (for one part of the study)

Who may not be able to join:

• People already classified as "Probable" or "Definite" ALS by the Awaji criteria before their first study assessment (for one part of the study)
• People who have significant loss of feeling in their weak or stiff limbs
• People who have significant pain in their muscles, joints, or nerves
• People who are unwilling or unable to give informed consent, or who lack the ability to do so
• People who are unable to carry out the tasks required by the study
• People currently taking the medications baclofen or benzodiazepines (a type of sedative/relaxant medication)
• People whose symptoms are already known to be caused by a condition other than ALS
• People with a history of other neurological conditions such as stroke, nerve damage (neuropathy), or muscle disease (myopathy)
• People who have been unclassified under the Awaji system or who have a confirmed condition that mimics ALS

Note: Being part of another treatment clinical trial is not a reason to be excluded from this study, as this study is not expected to interfere with other treatments.

Important: Always verify eligibility with the trial site directly before applying.