Motor Neurone Disease Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
People with ALS, ALS-FTD, or a similar neurodegenerative disease:
- People who have received a formal diagnosis of ALS (at any level of certainty, based on established diagnostic guidelines) or a similar neurodegenerative disease.
- People who are willing to give their consent to participate, or to give assent if muscle weakness caused by their disease makes signing consent difficult.
Spouses/domestic partners of people with ALS/ALS-FTD, or people with a family history of ALS/ALS-FTD or a similar disease:
- People who have never personally had ALS, ALS-FTD, or any other motor neuron disease.
- People whose family history of ALS or ALS-FTD involves a relative who is a first, second, or third degree blood relative (such as a parent, sibling, grandparent, aunt, uncle, or cousin).
- People who are willing to give their consent to participate.
Who may not be able to join:
People with ALS, ALS-FTD, or a similar neurodegenerative disease:
- People who have another medical condition that makes it unclear whether their neurological symptoms are caused by a neurodegenerative disease or something else entirely.
- People whose cognitive or mental capacity would prevent them from safely cooperating with a spinal fluid sample (lumbar puncture) or a standard blood draw.
- People who have a higher-than-normal risk of bleeding complications, or who have an allergy to the local anaesthetic or skin-cleaning solution used during a lumbar puncture.
Spouses/domestic partners or people with a family history of ALS/ALS-FTD:
- People whose cognitive or mental capacity would prevent them from safely cooperating with a lumbar puncture or a standard blood draw.
- People who have a higher-than-normal risk of bleeding complications, or who have an allergy to the local anaesthetic or skin-cleaning solution used during a lumbar puncture.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Blood serum collection; Blood plasma collection; Cerebrospinal fluid collection
Can't join this trial?
Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.