Phase 2 Ovarian Cancer Trial, Recruiting NCT05123807 Sponsor: M.D. Anderson Cancer Center Condition: Ovarian Cancer
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Phase 2 Ovarian Cancer Trial, Recruiting

NCT05123807
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with recurrent primary mucinous ovarian cancer, confirmed through laboratory testing of a tissue or cell sample
  • People aged 18 or older
  • People who are reasonably able to carry out daily activities (assessed using a standard health scale, confirm with trial site)
  • People whose blood counts and organ function meet specific levels when tested within 30 days before registering — including white blood cell counts, platelet counts, and liver and kidney function readings
  • People who have had their last chemotherapy or radiation treatment more than 2 weeks before joining (or more than 6 weeks if the treatment was bevacizumab)
  • People who are willing and able to sign an informed consent form, either themselves or through a legally authorised representative

Who may not be able to join:

  • People who are currently taking part in another experimental treatment trial, or who have received an unapproved experimental treatment within 30 days before the procedure
  • People whose mucinous tumour has been confirmed by pathology to have originated from somewhere other than the gynaecological system
  • People with known active cancer spread to the brain or central nervous system
  • People with a known allergy or sensitivity to cisplatin or any of its ingredients
  • People with an uncontrolled illness such as an active infection, unstable heart condition, unmanaged heart rhythm problems, or mental health or personal circumstances that may affect participation
  • People who are currently pregnant or breastfeeding
  • People with moderate to severe nerve damage in their hands or feet (confirm with trial site)
  • People who have previously had an organ or tissue transplant from another person
  • People who have previously had a specific type of chemotherapy delivered directly into the abdomen (HIPEC or intraperitoneal chemotherapy)
  • People with known large areas of cancer spread outside the abdomen and pelvis
  • People with moderate to severe hearing loss or ringing in the ears

Note: People with a history of another cancer may still be considered eligible, depending on whether that cancer or its treatment could affect the safety or results of this trial — the trial site would assess this individually.


Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Aaron Shafer, MD, M.D. Anderson Cancer Center

Phone: 832-885-6133

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
7 January 2022
Est. completion
2 February 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To estimate progression-free survival (PFS) after secondary cytoreductive surgery and HIPEC for women with recurrent primary mucinous ovarian cancer

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov