Phase 2 Breast Cancer Trial, Recruiting NCT05130801 Sponsor: Memorial Sloan Kettering Cancer Center Condition: Breast Cancer
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Phase 2 Breast Cancer Trial, Recruiting

NCT05130801
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 years or older
  • People who have been diagnosed with primary breast cancer confirmed by biopsy (classified as BI-RADS 6, meaning cancer is confirmed)
  • People whose tumour is at an early to intermediate stage (Tis, T1, or T2) and measures more than 1 cm in size
  • People whose planned surgery involves removing only part of the breast (known as breast-conserving surgery)
  • People who have not yet received any treatment for this cancer
  • People who are in reasonably good general health, able to carry out daily activities with little or no limitation (confirm with trial site)

Who may not be able to join:

  • People with a life expectancy of less than 3 months
  • People who are currently pregnant or breastfeeding
  • People with known spread of cancer to the liver, any liver tumours (whether cancerous or non-cancerous), a condition affecting the bile ducts from birth (biliary atresia), ongoing liver disease, or cirrhosis (serious liver scarring)
  • People with known moderate liver impairment — this applies to phase I of the trial, and may apply to phase IIa depending on safety findings from phase I (confirm with trial site)
  • People with a known allergy or sensitivity to a substance called indocyanine green (a dye used in medical imaging)
  • People who do not have the capacity to make their own informed decisions

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Clarissa Lin, MD, Memorial Sloan Kettering Cancer Center

Phone: 646-888-5119

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
19 November 2021
Est. completion
1 November 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Dose-limiting toxicity (DLT); Visualization of a lesion with pHLIP® ICG (Phase II)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov