Stroke Trial, Recruiting NCT05167786 Sponsor: Shirley Ryan AbilityLab Condition: Stroke
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Stroke Trial, Recruiting

NCT05167786
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • Adults aged 18 years or older
  • People who are willing and able to give written consent and follow the study procedures
  • People who had their stroke at least 6 months ago
  • People who have weakness or paralysis on one side of the body caused by a single stroke
  • People who need continuous or intermittent support from one person to help with balance and coordination when walking
  • People who are not currently receiving regular physical therapy
  • People whose doctor has approved their participation

Who may not be able to join:

  • People who have problems with coordination and balance caused by ataxia
  • People who have had more than one stroke
  • People who have had Botox injections in a leg within the last 4 months
  • People with a high level of muscle stiffness or spasticity in a leg, as measured by a clinical scoring tool (confirm with trial site)
  • People who are pregnant or breastfeeding
  • People who use an implanted heart device such as a pacemaker, defibrillator, or heart pump, or an implanted pump used to reduce muscle stiffness
  • People with active pressure sores or wounds on the skin
  • People with bone fractures that have not fully healed
  • People with nerve damage in the limbs (peripheral neuropathy)
  • People with painful joint or muscle problems due to an active injury or infection
  • People with severe tightening of muscles or tendons in the legs that limits movement
  • People with a medical illness that limits their ability to walk
  • People with an active urinary tract infection
  • People with significant depression, psychiatric conditions, or ongoing drug misuse
  • People with active cancer, or who have been in cancer remission for less than 5 years
  • People with a bone, joint, or surgical issue in a leg that would affect their ability to use it
  • People with a traumatic brain injury or other neurological condition that could affect the study results

For the brain stimulation (TMS) part of the study only, people may also not be able to join if they:

  • Are taking medications known to increase or decrease how active the brain's movement system is (confirm specific medications with trial site)
  • Have an implanted cardiac pacemaker
  • Have any metal implants in the head or face
  • Experience recurring headaches with no known cause
  • Have had a seizure unrelated to their stroke, or have epilepsy
  • Have any abnormalities or fractures in the skull
  • Have had a concussion within the last 6 months
  • Have unstable heart, breathing, or metabolic conditions such as uncontrolled high blood pressure, uncontrolled diabetes, irregular heartbeat, or severe chronic lung disease

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 15 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Arun Jayaraman, PT, PhD, Shirley Ryan AbilityLab

Phone: 312-238-7111

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Shirley Ryan AbilityLab
Registry
ClinicalTrials.gov
Start date
1 March 2022
Est. completion
31 July 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change in Gait Symmetry

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 15 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov