Phase 2 Lymphoma Trial, Recruiting NCT05183854 Sponsor: University of Utah Condition: Lymphoma
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Phase 2 Lymphoma Trial, Recruiting

NCT05183854
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Naive Cohort (people who have never been treated for CLL):

  • People who have been officially diagnosed with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) according to 2018 international medical guidelines
  • People aged 18 years or older
  • People who have never received any treatment for CLL

Venetoclax-Treatment Cohort (people previously treated with venetoclax):

  • People who have been officially diagnosed with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL) according to 2018 international medical guidelines
  • People who have taken the drug venetoclax (at any dose) for at least 12 months, with the last dose taken no more than 12 months before registering for the trial

Who may not be able to join:

  • People who have had a severe allergic reaction to a pneumococcal (pneumonia) vaccine in the past
  • People who have received a specific type of pneumococcal vaccine (called PCV13 or PCV20) within the last five years (note: people who received a different pneumococcal vaccine called PPSV23 at least one year ago, and no other pneumococcal vaccine, may still be eligible — confirm with trial site)
  • People who currently have an active infection being treated with antibiotic medication
  • People who have used immune-suppressing medications within 14 days of starting the trial, with some exceptions for certain low-dose or locally applied steroids (confirm with trial site)
  • People with another illness or condition that the treating doctor believes would negatively affect their ability to take part in the trial

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Daniel Ermann, MD, Huntsman Cancer Institute/ University of Utah

Phone: 801-587-4713

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Registry
ClinicalTrials.gov
Start date
31 January 2022
Est. completion
1 March 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of patients who achieve the protocol defined change in antibody titers

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov